Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL069256-02
Application #
6684141
Study Section
Hematology Subcommittee 2 (HEM)
Program Officer
Evans, Gregory
Project Start
2002-12-01
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$381,100
Indirect Cost
Name
Thomas Jefferson University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
053284659
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Steering Committee Of The Blood And Marrow Transplant Clinical Trials Network (2016) The Blood and Marrow Transplant Clinical Trials Network: An Effective Infrastructure for Addressing Important Issues in Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant 22:1747-1757
Bernardini, Laura; Alesi, Viola; Loddo, Sara et al. (2010) High-resolution SNP arrays in mental retardation diagnostics: how much do we gain? Eur J Hum Genet 18:178-85
Adachi, Kazuhiko; Ding, Min; Asakura, Toshio et al. (2009) Relationship between beta4 hydrogen bond and beta6 hydrophobic interactions during aggregate, fiber or crystal formation in oversaturated solutions of hemoglobin A and S. Arch Biochem Biophys 481:137-44
Battistella, Stefania; Damin, Francesco; Chiari, Marcella et al. (2008) Genotyping beta-globin gene mutations on copolymer-coated glass slides with the ligation detection reaction. Clin Chem 54:1657-63
Adachi, Kazuhiko; Ding, Min; Surrey, Saul (2008) Role of the beta4Thr-beta73Asp hydrogen bond in HbS polymer and domain formation from multinucleate-containing clusters. Biochemistry 47:5441-9
Adachi, Kazuhiko; Zhao, Yi; Lakka, Vinaysagar et al. (2007) Assembly of recently translated full-length and C-terminal truncated human gamma-globin chains with a pool of alpha-globin chains to form Hb F in a cell-free system. Arch Biochem Biophys 463:60-7
Fortina, Paolo; Kricka, Larry J; Graves, David J et al. (2007) Applications of nanoparticles to diagnostics and therapeutics in colorectal cancer. Trends Biotechnol 25:145-52
Keller, M A; Addya, S; Vadigepalli, R et al. (2006) Transcriptional regulatory network analysis of developing human erythroid progenitors reveals patterns of coregulation and potential transcriptional regulators. Physiol Genomics 28:114-28
Akbar, Mohammed G K; Tamura, Yutaka; Ding, Min et al. (2006) Inhibition of hemoglobin S polymerization in vitro by a novel 15-mer EF-helix beta73 histidine-containing peptide. Biochemistry 45:8358-67
Adachi, Kazuhiko; Ding, Min; Surrey, Saul et al. (2006) The Hb A variant (beta73 Asp-->Leu) disrupts Hb S polymerization by a novel mechanism. J Mol Biol 362:528-38

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