The proposed project is a competing continuation of our National Library of Medicine research grant to study medical knowledge base construction as a discipline (ROl LM04622). Unless we determine the most efficient and useful methods for knowledge base construction and maintenance, the future of medical expert systems will be bleak. Our previous work explored techniques for multi-centric creation of medical knowledge base entries. During the proposed extension, we will determine desiderata for selecting individuals to be knowledge base builders and maintainers, evaluate the variability in the way physicians construct knowledge bases, and determine how semi-automated tools can assist in knowledge base construction and maintenance. Our studies will focus on the QMR KB as a prototype of medical diagnostic derision support programs. It is likely that the American College of Physicians will adopt this KB as the seed for a national medical knowledge base in the near future.

Agency
National Institute of Health (NIH)
Institute
National Library of Medicine (NLM)
Type
Research Project (R01)
Project #
5R01LM004622-06
Application #
3373884
Study Section
Biomedical Library and Informatics Review Committee (BLR)
Project Start
1987-09-30
Project End
1994-06-30
Budget Start
1993-02-01
Budget End
1994-06-30
Support Year
6
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Giuse, D A; Giuse, N B; Miller, R A (1995) Evaluation of long-term maintenance of a large medical knowledge base. J Am Med Inform Assoc 2:297-306
Miller, R A (1994) Medical diagnostic decision support systems--past, present, and future: a threaded bibliography and brief commentary. J Am Med Inform Assoc 1:8-27
Giuse, D A; Giuse, N B; Miller, R A (1993) Consistency enforcement in medical knowledge base construction. Artif Intell Med 5:245-52
Giuse, N B; Giuse, D A; Bankowitz, R A et al. (1993) Comparing contents of a knowledge base to traditional information sources. Proc Annu Symp Comput Appl Med Care :626-30
Giuse, N B; Giuse, D A; Miller, R A et al. (1993) Evaluating consensus among physicians in medical knowledge base construction. Methods Inf Med 32:137-45
Giuse, D A; Giuse, N B; Miller, R A (1991) A tool for the computer-assisted creation of QMR medical knowledge base disease profiles. Proc Annu Symp Comput Appl Med Care :978-9
Giuse, D A; Giuse, N B; Bankowitz, R A et al. (1991) Heuristic determination of quantitative data for knowledge acquisition in medicine. Comput Biomed Res 24:261-72
Miller, R A; Jamnback, L; Giuse, N B et al. (1991) Extending the capabilities of diagnostic decision support programs through links to bibliographic searching: addition of ""canned MeSH logic"" to the Quick Medical Reference (QMR) program for use with Grateful Med. Proc Annu Symp Comput Appl Med Care :150-5
Miller, R A; Giuse, N B (1991) Medical knowledge bases. Acad Med 66:15-7
Miller, R A; Masarie Jr, F E (1989) Use of the Quick Medical Reference (QMR) program as a tool for medical education. Methods Inf Med 28:340-5