There is now sufficient evidence to state that season of birth is associated with the risk for schizophrenia. There is also some evidence suggesting that the season of birth phenomenon may be characteristic of only one subgroup of patients. The objective of this epidemiologic research is to determine whether schizophrenic patients born during the winter months of December, January and February are different from schizophrenic patients born during the other months of the year. The methods of this research are as follows: 1. Schizophrenic patients will be identified by screening several psychiatric facilities in Maryland. 2. Schizophrenics born during the winter months of December, January and February will be compared to schizophrenic patients born during the other months of the year to determine whether they differ in any of the following ways: pre-morbid characteristics, clinical manifestation, and age at first hospitalization.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH035712-03
Application #
3375734
Study Section
(SRC)
Project Start
1983-05-01
Project End
1986-04-30
Budget Start
1985-05-01
Budget End
1986-04-30
Support Year
3
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Muntaner, C; Wolyniec, P; McGrath, J et al. (1998) Arrest among psychotic inpatients: assessing the relationship to diagnosis, gender, number of admissions, and social class. Soc Psychiatry Psychiatr Epidemiol 33:274-82
Muntaner, C; Wolyniec, P; McGrath, J et al. (1995) Differences in social class among psychotic patients at inpatient admission. Psychiatr Serv 46:176-8
Karayiorgou, M; Kasch, L; Lasseter, V K et al. (1994) Report from the Maryland Epidemiology Schizophrenia Linkage Study: no evidence for linkage between schizophrenia and a number of candidate and other genomic regions using a complex dominant model. Am J Med Genet 54:345-53
Melton, B; Liang, K Y; Pulver, A E (1994) Extended latent class approach to the study of familial/sporadic forms of a disease: its application to the study of the heterogeneity of schizophrenia. Genet Epidemiol 11:311-27
Pulver, A E; Karayiorgou, M; Wolyniec, P S et al. (1994) Sequential strategy to identify a susceptibility gene for schizophrenia: report of potential linkage on chromosome 22q12-q13.1: Part 1. Am J Med Genet 54:36-43
Pulver, A E; Karayiorgou, M; Lasseter, V K et al. (1994) Follow-up of a report of a potential linkage for schizophrenia on chromosome 22q12-q13.1: Part 2. Am J Med Genet 54:44-50
Muntaner, C; Wolyniec, P; McGrath, J et al. (1994) Psychotic inpatients' social class and their first admission to state or private psychiatric Baltimore hospitals. Am J Public Health 84:287-9
Muntaner, C; Pulver, A E; McGrath, J et al. (1993) Work environment and schizophrenia: an extension of the arousal hypothesis to occupational self-selection. Soc Psychiatry Psychiatr Epidemiol 28:231-8
Pulver, A E; Liang, K Y; Wolyniec, P S et al. (1992) Season of birth of siblings of schizophrenic patients. Br J Psychiatry 160:71-5
Wolyniec, P S; Pulver, A E; McGrath, J A et al. (1992) Schizophrenia: gender and familial risk. J Psychiatr Res 26:17-27

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