Research on AIDS and AIDS-related complexes (ARC) indicates that the disease is contracted by exposure to HTLV-III carried by an infected person. Numerous risk-factor studies also indicate that homosexually active men with multiple partners who engage in sex activities permitting HTLV-III exposure are at greatest risk for AIDS and ARC. The study of interventions which alter the behavior of high-risk individuals will lead to the development of prevention programs that reduce AIDS prevalence. The purpose of the proposed project is to evaluate the impact of an AIDS risk-behavior reduction program for homosexually active, at-risk, but apparently healthy males. Ninety subjects will be randomly assigned to either an experimental or waiting-list control condition. Following assessment on a range of self-monitoring, self-report and behavioral measures, experimental group subjects will receive a 12-session behavioral training intervention to reduce casual, high-risk sexual encounters. Training will include self-management (control) skills, assertion training to refuse high-risk propositions, risk reduction education, and skills training to promote stable rather than promiscuous relationships. Following treatment, experimental group subjects will be compared with controls on multiple measures of risk behavior, including frequency of casual sex encounters, type of sex activities, drug use, depression, anxiety, and health-related characteristics. The treatment will then be replicated with those subjects originally assigned to the control group and all subjects will be assessed at one-year follow-up to determine maintenance of behavior change. Contingent upon successful findings, a detailed training protocol manual will then be developed and distributed to other investigators and to public health agencies. This activity is intended to promote efficient, rapid dissemination of study procedures to other scientists, applied researchers, and health agencies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH041800-02
Application #
3380618
Study Section
(LCRA)
Project Start
1986-07-15
Project End
1987-12-31
Budget Start
1987-07-01
Budget End
1987-12-31
Support Year
2
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Mississippi Medical Center
Department
Type
Schools of Medicine
DUNS #
928824473
City
Jackson
State
MS
Country
United States
Zip Code
39216
Kelly, J A (1994) Sexually transmitted disease prevention approaches that work. Interventions to reduce risk behavior among individuals, groups, and communities. Sex Transm Dis 21:S73-5
Kelly, J A; Murphy, D A; Washington, C D et al. (1994) The effects of HIV/AIDS intervention groups for high-risk women in urban clinics. Am J Public Health 84:1918-22
Kelly, J A; Murphy, D A; Sikkema, K J et al. (1993) Psychological interventions to prevent HIV infection are urgently needed. New priorities for behavioral research in the second decade of AIDS. Am Psychol 48:1023-34
Kalichman, S C; Kelly, J A; Hunter, T L et al. (1993) Culturally tailored HIV-AIDS risk-reduction messages targeted to African-American urban women: impact on risk sensitization and risk reduction. J Consult Clin Psychol 61:291-5
Kelly, J A; Murphy, D A (1992) Psychological interventions with AIDS and HIV: prevention and treatment. J Consult Clin Psychol 60:576-85
Kelly, J A; Murphy, D A; Bahr, G R et al. (1992) AIDS/HIV risk behavior among the chronic mentally ill. Am J Psychiatry 149:886-9
Kelly, J A; St Lawrence, J S; Brasfield, T L (1991) Predictors of vulnerability to AIDS risk behavior relapse. J Consult Clin Psychol 59:163-6
Kelly, J A; Murphy, D A (1991) Some lessons learned about risk reduction after ten years of the HIV/AIDS epidemic. AIDS Care 3:251-7
Kelly, J A; St Lawrence, J S (1990) The impact of community-based groups to help persons reduce HIV infection risk behaviours. AIDS Care 2:25-36
Kelly, J A; St Lawrence, J S; Brasfield, T L et al. (1990) Psychological factors that predict AIDS high-risk versus AIDS precautionary behavior. J Consult Clin Psychol 58:117-20

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