This is a proposal to collect longitudinal follow-up (second panel) data on a sub-sample of families with same-sex siblings (719 original families, 450 follow-up families) studied during 1988-1990. The original families consisted of six groups, (1) MZ twins, (2) DZ twins, (3) Step families with full siblings, (4) Step families with half siblings, (5) Step families with genetically unrelated children, (6) Non-divorced families with full siblings. A major goal of the initial project was to estimate shared environment influences and additive and non-additive genetic influences on environmental measures. The particular configuration of families was chosen to maximize the conceptual power of the design rather than precisely estimated the magnitude of effects on a representative sample of the U.S. The sample, however, is a very broad one relative to those used in other developmental studies. In the follow-up study the investigator plan to assess 7 domains of the environment, Parent-child interactions (7 measures, including a videotaped segment), sibling interaction, (5 measures, including a videotapes segment), relationships with non-residential parent(1 instrument), peer relationships (1 instrument), peer relationships (1 instrument), other (Life Event checklist, Social support). Also included are three domains of outcome measures; Mental health/Illness indicators (5 measures, 1 videotaped segment), Personality Developmental strengths (7 measures, 1 videotaped), and Child pubertal status (1 measure). A number of characteristics of the family that may moderate non-shared environmental effects are also assessed; General stressors (1 measure) and Martial conflict (4 measures, 1 videotaped segment). In addition, standard social and demographic information is gathered. The data will be collected by interviewers hired and trained by the National Opinion Research Center (NORC) on two occasion one week apart. The purpose of a longitudinal component is to allow the investigators to address a series of complex questions regarding the dynamics of change on the wide variety of measures proposed(e.g., does the relative influence of heredity and environment on change over time?)

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH048825-02
Application #
3388333
Study Section
Special Emphasis Panel (SRCM)
Project Start
1991-09-30
Project End
1995-08-31
Budget Start
1992-09-30
Budget End
1993-08-31
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost
Name
George Washington University
Department
Type
Schools of Medicine
DUNS #
City
Washington
State
DC
Country
United States
Zip Code
20052
Marceau, Kristine; Knopik, Valerie S; Neiderhiser, Jenae M et al. (2016) Adolescent age moderates genetic and environmental influences on parent-adolescent positivity and negativity: Implications for genotype-environment correlation. Dev Psychopathol 28:149-66
Marceau, Kristine; Horwitz, Briana N; Narusyte, Jurgita et al. (2013) Gene-environment correlation underlying the association between parental negativity and adolescent externalizing problems. Child Dev 84:2031-46
Marceau, Kristine; Humbad, Mikhila N; Burt, S Alexandra et al. (2012) Observed externalizing behavior: a developmental comparison of genetic and environmental influences across three samples. Behav Genet 42:30-9
Ge, Xiaojia; Natsuaki, Misaki N; Neiderhiser, Jenae M et al. (2009) The longitudinal effects of stressful life events on adolescent depression are buffered by parent-child closeness. Dev Psychopathol 21:621-35
Natsuaki, Misaki N; Ge, Xiaojia; Reiss, David et al. (2009) Aggressive behavior between siblings and the development of externalizing problems: evidence from a genetically sensitive study. Dev Psychol 45:1009-18
Harakeh, Zeena; Neiderhiser, Jenae M; Spotts, Erica L et al. (2008) Genetic factors contribute to the association between peers and young adults smoking: univariate and multivariate behavioral genetic analyses. Addict Behav 33:1113-22
Dimas, Christos; Reiss, David; Neiderhiser, Jenae (2008) Summaries of the Sixth Annual Poster Session of the American Psychoanalytic Association: part I. Triangular relationships in adolescence predict adult psychopathology: an empirical validation of the Oedipus complex? J Am Psychoanal Assoc 56:1342-8
Neiderhiser, Jenae M; Reiss, David; Hetherington, E Mavis (2007) The Nonshared Environment in Adolescent Development (NEAD) project: a longitudinal family study of twins and siblings from adolescence to young adulthood. Twin Res Hum Genet 10:74-83
Neiderhiser, Jenae M; Reiss, David; Pedersen, Nancy L et al. (2004) Genetic and environmental influences on mothering of adolescents: a comparison of two samples. Dev Psychol 40:335-51
Neiderhiser, J M; Reiss, D; Hetherington, E M et al. (1999) Relationships between parenting and adolescent adjustment over time: genetic and environmental contributions. Dev Psychol 35:680-92

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