The major purpose of the study is to conduct a controlled trial of cognitive processing therapy (CPT) to determine the relative efficacy of direct intervention with attributions and beliefs plus exposure when compared to prolonged exposure only, or a minimal attention control. The role of cognitions, particularly the victim's perception of the meaning of the event, will be studied as it relates to an information processing theory of crime-based PTSD. The role of cognitions will be examined within the context of treatment such that it will he possible to determine whether cognitions change as a result of treatment and whether certain types of cognitions are differentially related to therapy outcome. During assessments, participants will complete symptom inventories, cognitive scales, and a diagnostic interview. Research participants will consist of 120 rape victims meeting the criteria for PTSD for at least three months following their assault Participants will be randomly assigned to one of the three conditions: CPT, prolonged exposure only, or the minimal attention condition. Participants in the latter group will be reassigned to either the CPT or prolonged exposure conditions. Participants will be assessed pre- treatment, post-treatment, and three months following the completion of treatment.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH051509-02
Application #
2250749
Study Section
Violence and Traumatic Stress Review Committee (VTS)
Project Start
1994-05-01
Project End
1999-04-30
Budget Start
1995-05-01
Budget End
1996-04-30
Support Year
2
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Missouri-St. Louis
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
City
Saint Louis
State
MO
Country
United States
Zip Code
63121
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Scioli-Salter, Erica R; Johnides, Benjamin D; Mitchell, Karen S et al. (2016) Depression and dissociation as predictors of physical health symptoms among female rape survivors with posttraumatic stress disorder. Psychol Trauma 8:585-91
Iverson, Katherine M; King, Matthew W; Cunningham, Katherine C et al. (2015) Rape survivors' trauma-related beliefs before and after Cognitive processing therapy: associations with PTSD and depression symptoms. Behav Res Ther 66:49-55
Galovski, Tara E; Elwood, Lisa S; Blain, Leah M et al. (2014) Changes in Anger in Relationship to Responsivity to PTSD Treatment. Psychol Trauma 6:56-64
Jayawickreme, Nuwan; Cahill, Shawn P; Riggs, David S et al. (2014) Primum non nocere (first do no harm): symptom worsening and improvement in female assault victims after prolonged exposure for PTSD. Depress Anxiety 31:412-9

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