EXCEED THE SPACE PROVIDED. This proposal will incorporate: (1) a one-year formative phase to assess youth (i.e., between 18 and 24 years old) preferences for web design and to develop state ofthe art web-based strategies promoting adoption ofHIV/STD prevention behavior; and (2) a two-year study to test the feasibility ofrecruiting, enrolling and retaining youth in a randomized, controlled trial to study the impact of: (a) peer support from chat room and bulletin boards and (b) tailored, interactive HIV/STD prevention messages and coping skills on knowledge, self-efficacy, outcome expectancies and behaviors related to condom use with sexual partners. During the first 6 months, investigators will conduct focus groups with youth to ascertain preferences for web-site design incorporating chat rooms, bulletin boards, and interactive components and to generate, modify and test ideas for tailored risk reduction messages that can be delivered online. Simultaneous to the focus groups and for 6 months thereafter, investigators will work with expert web designers, to translate design preferences to multiple Internet web pages. In months 13 through 31 ofthe project, we will implement a randomized controlled trial that will take place on the Internet. Youth between the ages of 18 and 24 who attend clinic sites in the Denver metropolitan area will be recruited to participate in the study. They will first complete an online, self-administeredbaseline assessment of condom knowledge, attitudes and practices. Participants will then be randomized to one ofthree study arms. In the first arm (control), participants will be directed to a web page with standard didactic messages about HIV/STD prevention. The second arm (social support) will direct participants to a web page on which they can take part in online chat rooms and post bulletin board messages about issues including, but not limited to, condom use. The third arm (tailored risk reduction options) will direct participants to a web page where they will receive personalized feedback, coping skills training, and.Iailored messages promoting condom use based on their responses to the baseline assessment, delivered by spokespersons we call role models. Through this effort we will explore whether we can recruit and retain an adequate sample of study participants; whether participants adhere to the randomized controlled trial protocol for logging on to web sites with assigned frequency (including baseline, intervention and follow-up log-ons); whether condom knowledge, self-efficacy,and outcome expectancies are affectedby: (a) peer support online and/or (b) tailored interactive messages; and whether condom use is affectedby: (a) peer support online and/or (b) tailored interactive messages. This revised proposal has three major changes from the first submission: it is a feasibility study, investigating whether an online trial for HIV/STD prevention is possible; it incorporates three rather than four study arms; and is a three rather than four year project. PERI~'ORNIANCESITE(S) (organization, city, state) AMC Cancer Research Center Denver, Colorado Denver Health and Hospital Authority Denver, Colorado Planned Parenthood ofthe Rocky Mountains (PPRM) Denver, Colorado KEY PERSONNEL ========================================Section End===========================================

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH063690-03
Application #
6838258
Study Section
Special Emphasis Panel (ZRG1-AARR-7 (01))
Program Officer
Pequegnat, Willo
Project Start
2003-01-01
Project End
2006-12-31
Budget Start
2005-01-01
Budget End
2005-12-31
Support Year
3
Fiscal Year
2005
Total Cost
$483,981
Indirect Cost
Name
University of Colorado Denver
Department
Family Medicine
Type
Schools of Medicine
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Bull, Sheana S; Levine, Deborah K; Black, Sandra R et al. (2012) Social media-delivered sexual health intervention: a cluster randomized controlled trial. Am J Prev Med 43:467-74
Bull, Sheana; Pratte, Katherine; Whitesell, Nancy et al. (2009) Effects of an Internet-based intervention for HIV prevention: the Youthnet trials. AIDS Behav 13:474-87
Bull, S S; Vallejos, D; Levine, D et al. (2008) Improving recruitment and retention for an online randomized controlled trial: experience from the Youthnet study. AIDS Care 20:887-93
Bull, Sheana Salyers; Phibbs, Stephanie; Watson, Sally et al. (2007) What do young adults expect when they go online? Lessons for development of an STD/HIV and pregnancy prevention website. J Med Syst 31:149-58