Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
7R01NS013799-08
Application #
3395330
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1989-01-01
Project End
1993-06-30
Budget Start
1989-01-01
Budget End
1989-06-30
Support Year
8
Fiscal Year
1988
Total Cost
Indirect Cost
Name
West Virginia University
Department
Type
School of Medicine & Dentistry
DUNS #
191510239
City
Morgantown
State
WV
Country
United States
Zip Code
26506
Gu, J; Royland, J E; Wiggins, R C et al. (1997) Selenium is required for normal upregulation of myelin genes in differentiating oligodendrocytes. J Neurosci Res 47:626-35
Grubinska, B; Laszkiewicz, I; Royland, J et al. (1994) Differentiation-specific demethylation of myelin associated glycoprotein gene in cultured oligodendrocytes. J Neurosci Res 39:233-42
Zhu, W; Wiggins, R C; Konat, G W (1994) Glucocorticoid-induced upregulation of proteolipid protein and myelin-associated glycoprotein genes in C6 cells. J Neurosci Res 37:208-12
Ye, P; Laszkiewicz, I; Wiggins, R C et al. (1994) Transcriptional regulation of myelin associated glycoprotein gene expression by cyclic AMP. J Neurosci Res 37:683-90
Yassini, P R; Wiggins, R C; Konat, G W (1993) Spatiotemporal expression of SCIP and myelin genes in rat brain during early postnatal development. Dev Neurosci 15:128-32
Royland, J E; Konat, G W; Wiggins, R C (1993) Myelin gene activation: a glucose sensitive critical period in development. J Neurosci Res 36:399-404
Royland, J E; Konat, G; Wiggins, R C (1993) Abnormal upregulation of myelin genes underlies the critical period of myelination in undernourished developing rat brain. Brain Res 607:113-6
Gu, J; Yassini, P; Goldberg, G et al. (1993) Cocaine cytotoxicity in serum-free environment: C6 glioma cell culture. Neurotoxicology 14:19-22
Wiggins, R C (1992) Pharmacokinetics of cocaine in pregnancy and effects on fetal maturation. Clin Pharmacokinet 22:85-93
Zhu, W; Kanoh, M; Ye, P et al. (1992) Retinoic acid-regulated expression of proteolipid protein and myelin-associated glycoprotein genes in C6 glioma cells. J Neurosci Res 31:745-50

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