Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS028695-07
Application #
2267097
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1990-08-01
Project End
1997-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Buck, Kenneth B; Schaefer, Andrew W; Schoonderwoert, Vincent T et al. (2017) Local Arp2/3-dependent actin assembly modulates applied traction force during apCAM adhesion site maturation. Mol Biol Cell 28:98-110
Zhang, Yalan; Zhang, Xiao-Feng; Fleming, Matthew R et al. (2016) Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating. Cell 165:434-448
Hyland, Callen; Mertz, Aaron F; Forscher, Paul et al. (2014) Dynamic peripheral traction forces balance stable neurite tension in regenerating Aplysia bag cell neurons. Sci Rep 4:4961
Hyland, Callen; Dufresne, Eric R; Dufrense, Eric R et al. (2014) Regeneration of Aplysia bag cell neurons is synergistically enhanced by substrate-bound hemolymph proteins and laminin. Sci Rep 4:4617
Mejean, Cecile O; Schaefer, Andrew W; Buck, Kenneth B et al. (2013) Elastic coupling of nascent apCAM adhesions to flowing actin networks. PLoS One 8:e73389
Yang, Qing; Zhang, Xiao-Feng; Van Goor, David et al. (2013) Protein kinase C activation decreases peripheral actin network density and increases central nonmuscle myosin II contractility in neuronal growth cones. Mol Biol Cell 24:3097-114
Craig, Erin M; Van Goor, David; Forscher, Paul et al. (2012) Membrane tension, myosin force, and actin turnover maintain actin treadmill in the nerve growth cone. Biophys J 102:1503-13
Van Goor, David; Hyland, Callen; Schaefer, Andrew W et al. (2012) The role of actin turnover in retrograde actin network flow in neuronal growth cones. PLoS One 7:e30959
Yang, Qing; Zhang, Xiao-Feng; Pollard, Thomas D et al. (2012) Arp2/3 complex-dependent actin networks constrain myosin II function in driving retrograde actin flow. J Cell Biol 197:939-56
Zhang, Xiao-Feng; Hyland, Callen; Van Goor, David et al. (2012) Calcineurin-dependent cofilin activation and increased retrograde actin flow drive 5-HT-dependent neurite outgrowth in Aplysia bag cell neurons. Mol Biol Cell 23:4833-48

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