Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS030147-03
Application #
2268207
Study Section
Special Emphasis Panel (ZRG1-NLS-1 (01))
Program Officer
Spinella, Giovanna M
Project Start
1992-09-30
Project End
1999-09-29
Budget Start
1994-09-30
Budget End
1999-09-29
Support Year
3
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Institute for Basic Research in Dev Disabil
Department
Type
DUNS #
167205090
City
Staten Island
State
NY
Country
United States
Zip Code
10314
Junaid, M A; Brooks, S S; Pullarkat, R K (2001) Specific substrate for CLN2 protease/tripeptidyl-peptidase I assay. Eur J Paediatr Neurol 5 Suppl A:63-8
Junaid, M A; Pullarkat, R K (2001) Biochemistry of neuronal ceroid lipofuscinoses. Adv Genet 45:93-106
He, X Y; Merz, G; Yang, Y Z et al. (2000) Function of human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase in androgen metabolism. Biochim Biophys Acta 1484:267-77
Junaid, M A; Clark, G M; Pullarkat, R K (2000) A lysosomal pepstatin-insensitive proteinase as a novel biomarker for breast carcinoma. Int J Biol Markers 15:129-34
Junaid, M A; Wu, G; Pullarkat, R K (2000) Purification and characterization of bovine brain lysosomal pepstatin-insensitive proteinase, the gene product deficient in the human late-infantile neuronal ceroid lipofuscinosis. J Neurochem 74:287-94
Junaid, M A; Sklower Brooks, S; Wisniewski, K E et al. (1999) A novel assay for lysosomal pepstatin-insensitive proteinase and its application for the diagnosis of late-infantile neuronal ceroid lipofuscinosis. Clin Chim Acta 281:169-76
Junaid, M A; Pullarkat, R K (1999) Increased brain lysosomal pepstatin-insensitive proteinase activity in patients with neurodegenerative diseases. Neurosci Lett 264:157-60
Mitchison, H M; Bernard, D J; Greene, N D et al. (1999) Targeted disruption of the Cln3 gene provides a mouse model for Batten disease. The Batten Mouse Model Consortium [corrected] Neurobiol Dis 6:321-34
Sleat, D E; Sohar, I; Pullarkat, P S et al. (1998) Specific alterations in levels of mannose 6-phosphorylated glycoproteins in different neuronal ceroid lipofuscinoses. Biochem J 334 ( Pt 3):547-51
Sleat, D E; Donnelly, R J; Lackland, H et al. (1997) Association of mutations in a lysosomal protein with classical late-infantile neuronal ceroid lipofuscinosis. Science 277:1802-5

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