GABA a Receptor Subunit Expression in Cerebellar Neurons - Ruth Siegel

Abstract

Funding Agency

Agency: National Institute of Health (NIH)
Institute: National Institute of Neurological Disorders and Stroke (NINDS)
Type: Research Project (R01)
Project #: 5R01NS031266-04
Application #: 2269215
Study Section: Neurological Sciences Subcommittee 1 (NLS)
Program Officer: Streicher, Eugene

Project Start: 1992-12-01
Project End: 1997-11-30
Budget Start: 1995-12-01
Budget End: 1997-11-30
Support Year: 4
Fiscal Year: 1996
Total Cost
Indirect Cost

Institution

Name: Case Western Reserve University
Department: Pharmacology
Type: Schools of Medicine
DUNS #: 077758407

City: Cleveland
State: OH
Country: United States
Zip Code: 44106

Related projects


NIH 2000 R01 NS	GABA-A Receptor Expression in Cerebellar Neurons Siegel, Ruth E. / Case Western Reserve University	$199,743
NIH 1999 R01 NS	GABA-A Receptor Expression in Cerebellar Neurons Siegel, Ruth E. / Case Western Reserve University
NIH 1998 R01 NS	GABA-A Receptor Expression in Cerebellar Neurons Siegel, Ruth E. / Case Western Reserve University
NIH 1997 R01 NS	GABA-A Receptor Expression in Cerebellar Neurons Siegel, Ruth E. / Case Western Reserve University
NIH 1996 R01 NS	GABA a Receptor Subunit Expression in Cerebellar Neurons Siegel, Ruth E. / Case Western Reserve University
NIH 1995 R01 NS	GABA a Receptor Subunit Expression in Cerebellar Neurons Siegel, Ruth E. / Case Western Reserve University
NIH 1994 R01 NS	GABA a Receptor Subunit Expression in Cerebellar Neurons Siegel, Ruth E. / Case Western Reserve University
NIH 1993 R01 NS	GABA-A Receptor Subunit Expression in Cultured Neurons Siegel, Ruth E. / Case Western Reserve University

Publications

Kumar, M; Luo, X; Quirk, P L et al. (2001) Antisense suppression of GABA(A) receptor beta subunit levels in cultured cerebellar granule neurons demonstrates their importance in receptor expression. J Neurochem 77:211-9

Raetzman, L T; Siegel, R E (1999) Immature granule neurons from cerebella of different ages exhibit distinct developmental potentials. J Neurobiol 38:559-70

Gault, L M; Siegel, R E (1998) NMDA receptor stimulation selectively initiates GABA(A) receptor delta subunit mRNA expression in cultured rat cerebellar granule neurons. J Neurochem 70:1907-15

Siegel, R E (1998) Developmental expression of cerebellar GABAA-receptor subunit mRNAs. Nature versus nurture. Perspect Dev Neurobiol 5:207-17

Gault, L M; Siegel, R E (1997) Expression of the GABAA receptor delta subunit is selectively modulated by depolarization in cultured rat cerebellar granule neurons. J Neurosci 17:2391-9

Nadler, L S; Raetzman, L T; Dunkle, K L et al. (1996) GABAA receptor subunit expression and assembly in cultured rat cerebellar granule neurons. Brain Res Dev Brain Res 97:216-25

Behringer, K A; Gault, L M; Siegel, R E (1996) Differential regulation of GABA A receptor subunit mRNAs in rat cerebellar granule neurons: importance of environmental cues. J Neurochem 66:1347-53

Nadler, L S; Guirguis, E R; Siegel, R E (1994) GABAA receptor subunit polypeptides increase in parallel but exhibit distinct distributions in the developing rat cerebellum. J Neurobiol 25:1533-44

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