Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS031271-02
Application #
2269219
Study Section
Neurology C Study Section (NEUC)
Project Start
1995-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Pediatrics
Type
Other Domestic Higher Education
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Norris, Andrew J; Whitelegge, Julian P; Yaghoubian, Arman et al. (2005) A novel mass spectrometric assay for the cerebroside sulfate activator protein (saposin B) and arylsulfatase A. J Lipid Res 46:2254-64
Whitelegge, J P; Ahn, V; Norris, A J et al. (2003) Characterization of a recombinant molecule covalently indistinguishable from human cerebroside-sulfate activator protein (CSAct or Saposin B). Cell Mol Biol (Noisy-le-grand) 49:799-807
Ahn, Victoria E; Faull, Kym F; Whitelegge, Julian P et al. (2003) Expression, purification, crystallization, and preliminary X-ray analysis of recombinant human saposin B. Protein Expr Purif 27:186-93
Ahn, Victoria E; Faull, Kym F; Whitelegge, Julian P et al. (2003) Crystal structure of saposin B reveals a dimeric shell for lipid binding. Proc Natl Acad Sci U S A 100:38-43
Whitelegge, Julian P; Gomez, Stephen M; Faull, Kym F (2003) Proteomics of membrane proteins. Adv Protein Chem 65:271-307
Behnam, Keyvan; Murray, Samuel S; Whitelegge, Julian P et al. (2002) Identification of the molecular chaperone alpha B-crystallin in demineralized bone powder and osteoblast-like cells. J Orthop Res 20:1190-6
Gomez, Stephen M; Nishio, John N; Faull, Kym F et al. (2002) The chloroplast grana proteome defined by intact mass measurements from liquid chromatography mass spectrometry. Mol Cell Proteomics 1:46-59
Fluharty, C B; Johnson, J; Whitelegge, J et al. (2001) Comparative lipid binding study on the cerebroside sulfate activator (saposin B). J Neurosci Res 63:82-9
Faull, K F; Higginson, J; Waring, A J et al. (2000) Hydrogen-deuterium exchange signature of porcine cerebroside sulfate activator protein. J Mass Spectrom 35:392-401
Whitelegge, J P; Penn, B; To, T et al. (2000) Methionine oxidation within the cerebroside-sulfate activator protein (CSAct or Saposin B). Protein Sci 9:1618-30

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