Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS031353-03
Application #
2269268
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1993-09-01
Project End
1997-08-31
Budget Start
1995-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Rosenberg, P A; Li, Y; Ali, S et al. (1999) Intracellular redox state determines whether nitric oxide is toxic or protective to rat oligodendrocytes in culture. J Neurochem 73:476-84
Wang, G J; Chung, H J; Schnuer, J et al. (1998) Dihydrokainate-sensitive neuronal glutamate transport is required for protection of rat cortical neurons in culture against synaptically released glutamate. Eur J Neurosci 10:2523-31
Wang, G J; Chung, H J; Schnuer, J et al. (1998) High affinity glutamate transport in rat cortical neurons in culture. Mol Pharmacol 53:88-96
Hartnett, K A; Stout, A K; Rajdev, S et al. (1997) NMDA receptor-mediated neurotoxicity: a paradoxical requirement for extracellular Mg2+ in Na+/Ca2+-free solutions in rat cortical neurons in vitro. J Neurochem 68:1836-45
Churchwell, K B; Wright, S H; Emma, F et al. (1996) NMDA receptor activation inhibits neuronal volume regulation after swelling induced by veratridine-stimulated Na+ influx in rat cortical cultures. J Neurosci 16:7447-57
Pawlikowska, L; Cottrell, S E; Harms, M B et al. (1996) Extracellular synthesis of cADP-ribose from nicotinamide-adenine dinucleotide by rat cortical astrocytes in culture. J Neurosci 16:5372-81
Blitzblau, R; Gupta, S; Djali, S et al. (1996) The glutamate transport inhibitor L-trans-pyrrolidine-2,4-dicarboxylate indirectly evokes NMDA receptor mediated neurotoxicity in rat cortical cultures. Eur J Neurosci 8:1840-52
Yonezawa, M; Back, S A; Gan, X et al. (1996) Cystine deprivation induces oligodendroglial death: rescue by free radical scavengers and by a diffusible glial factor. J Neurochem 67:566-73
Newcomer, T A; Rosenberg, P A; Aizenman, E (1995) Iron-mediated oxidation of 3,4-dihydroxyphenylalanine to an excitotoxin. J Neurochem 64:1742-8
Newcomer, T A; Rosenberg, P A; Aizenman, E (1995) TOPA quinone, a kainate-like agonist and excitotoxin is generated by a catecholaminergic cell line. J Neurosci 15:3172-7

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