BRN-4 - Role of A Pou-Domain in Brain Development

Crenshaw, E Bryan

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 5R01NS031674-04
• Application #: 2269631
• Study Section: Neurology C Study Section (NEUC)
• Project Start: 1994-01-01
• Project End: 1997-12-31
• Budget Start: 1996-01-01
• Budget End: 1996-12-31
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: University of Pennsylvania
• Department: Neurology
• Type: Schools of Medicine
• DUNS #: 042250712
• City: Philadelphia
• State: PA
• Country: United States
• Zip Code: 19104

Publications

Phippard, D; Boyd, Y; Reed, V et al. (2000) The sex-linked fidget mutation abolishes Brn4/Pou3f4 gene expression in the embryonic inner ear. Hum Mol Genet 9:79-85

Phippard, D; Lu, L; Lee, D et al. (1999) Targeted mutagenesis of the POU-domain gene Brn4/Pou3f4 causes developmental defects in the inner ear. J Neurosci 19:5980-9

Phippard, D; Heydemann, A; Lechner, M et al. (1998) Changes in the subcellular localization of the Brn4 gene product precede mesenchymal remodeling of the otic capsule. Hear Res 120:77-85