Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS033118-05
Application #
6539792
Study Section
Special Emphasis Panel (ZRG1-MDCN-3 (05))
Program Officer
Leblanc, Gabrielle G
Project Start
1995-04-04
Project End
2006-04-30
Budget Start
2002-05-01
Budget End
2003-04-30
Support Year
5
Fiscal Year
2002
Total Cost
$277,375
Indirect Cost
Name
Tufts University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Shen, Yiping; Meiri, Karina (2013) GAP-43 dependency defines distinct effects of netrin-1 on cortical and spinal neurite outgrowth and directional guidance. Int J Dev Neurosci 31:11-20
Gupta, Shailesh Kumar; Meiri, Karina F; Mahfooz, Kashif et al. (2010) Coordination between extrinsic extracellular matrix cues and intrinsic responses to orient the centrosome in polarizing cerebellar granule neurons. J Neurosci 30:2755-66
Nguyen, Lilly; He, Qin; Meiri, Karina F (2009) Regulation of GAP-43 at serine 41 acts as a switch to modulate both intrinsic and extrinsic behaviors of growing neurons, via altered membrane distribution. Mol Cell Neurosci 41:62-73
Mishra, Rashmi; Gupta, Shailesh Kumar; Meiri, Karina F et al. (2008) GAP-43 is key to mitotic spindle control and centrosome-based polarization in neurons. Cell Cycle 7:348-57
Shen, Yiping; Mishra, Rashmi; Mani, Shyamala et al. (2008) Both cell-autonomous and cell non-autonomous functions of GAP-43 are required for normal patterning of the cerebellum in vivo. Cerebellum 7:451-66
Rekart, Jerome L; Meiri, Karina; Routtenberg, Aryeh (2005) Hippocampal-dependent memory is impaired in heterozygous GAP-43 knockout mice. Hippocampus 15:1-7
Meiri, Karina F (2005) Lipid rafts and regulation of the cytoskeleton during T cell activation. Philos Trans R Soc Lond B Biol Sci 360:1663-72
Freudenthal, Ramiro; Romano, Arturo; Routtenberg, Aryeh (2004) Transcription factor NF-kappaB activation after in vivo perforant path LTP in mouse hippocampus. Hippocampus 14:677-83
Shen, Yiping; Mani, Shyamala; Meiri, Karina F (2004) Failure to express GAP-43 leads to disruption of a multipotent precursor and inhibits astrocyte differentiation. Mol Cell Neurosci 26:390-405
Shen, Yiping; Mani, Shyamala; Donovan, Stacy L et al. (2002) Growth-associated protein-43 is required for commissural axon guidance in the developing vertebrate nervous system. J Neurosci 22:239-47

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