Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS033186-03
Application #
2271819
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1994-08-01
Project End
1998-04-30
Budget Start
1996-08-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Neurology
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Mohamed, Habib A; Mosier, Dennis R; Zou, Ling L et al. (2002) Immunoglobulin Fc gamma receptor promotes immunoglobulin uptake, immunoglobulin-mediated calcium increase, and neurotransmitter release in motor neurons. J Neurosci Res 69:110-6
Mosier, D R; Siklos, L; Appel, S H (2000) Resistance of extraocular motoneuron terminals to effects of amyotrophic lateral sclerosis sera. Neurology 54:252-5
Siklos, L; Engelhardt, J I; Alexianu, M E et al. (1998) Intracellular calcium parallels motoneuron degeneration in SOD-1 mutant mice. J Neuropathol Exp Neurol 57:571-87
Alexianu, M E; Robbins, E; Carswell, S et al. (1998) 1Alpha, 25 dihydroxyvitamin D3-dependent up-regulation of calcium-binding proteins in motoneuron cells. J Neurosci Res 51:58-66
Smith, R G; Henry, Y K; Mattson, M P et al. (1998) Presence of 4-hydroxynonenal in cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis. Ann Neurol 44:696-9
La Bella, V; Goodman, J C; Appel, S H (1997) Increased CSF glutamate following injection of ALS immunoglobulins. Neurology 48:1270-2
Colom, L V; Alexianu, M E; Mosier, D R et al. (1997) Amyotrophic lateral sclerosis immunoglobulins increase intracellular calcium in a motoneuron cell line. Exp Neurol 146:354-60
Engelhardt, J I; Siklos, L; Appel, S H (1997) Altered calcium homeostasis and ultrastructure in motoneurons of mice caused by passively transferred anti-motoneuronal IgG. J Neuropathol Exp Neurol 56:21-39
Engelhardt, J I; Siklos, L; Appel, S H (1997) Immunization of guinea pigs with human choline acetyltransferase induces selective lower motoneuron destruction. J Neuroimmunol 78:57-68
Smith, R G; Kimura, F; Harati, Y et al. (1995) Altered muscle calcium channel binding kinetics in autoimmune motoneuron disease. Muscle Nerve 18:620-7

Showing the most recent 10 out of 12 publications