Monoclonal Antibody That Induces Neuronal Apoptosis

Bredesen, Dale E.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 5R01NS033376-05
• Application #: 6139512
• Study Section: Neurological Sciences Subcommittee 1 (NLS)
• Program Officer: Murphy, Diane
• Project Start: 1997-01-01
• Project End: 2001-12-31
• Budget Start: 2000-01-01
• Budget End: 2001-12-31
• Support Year: 5
• Fiscal Year: 2000
• Total Cost: $298,383

Institution

• Name: Buck Institute for Age Research
• DUNS #: 800772162
• City: Novato
• State: CA
• Country: United States
• Zip Code: 94945

Publications

Zhang, Junli; Spilman, Patricia; Chen, Sylvia et al. (2013) The small co-chaperone p23 overexpressing transgenic mouse. J Neurosci Methods 212:190-4

Rao, Rammohan V; Descamps, Olivier; John, Varghese et al. (2012) Ayurvedic medicinal plants for Alzheimer's disease: a review. Alzheimers Res Ther 4:22

Sultana, Rukhsana; Robinson, Renã A S; Lange, Miranda Bader et al. (2012) Do proteomics analyses provide insights into reduced oxidative stress in the brain of an Alzheimer disease transgenic mouse model with an M631L amyloid precursor protein substitution and thereby the importance of amyloid-beta-resident methionine 35 in Alz Antioxid Redox Signal 17:1507-14

Poksay, Karen S; Banwait, Surita; Crippen, Danielle et al. (2012) The small chaperone protein p23 and its cleaved product p19 in cellular stress. J Mol Neurosci 46:303-14

Mukherjee, Abhisek; Soto, Claudio (2011) Role of calcineurin in neurodegeneration produced by misfolded proteins and endoplasmic reticulum stress. Curr Opin Cell Biol 23:223-30

Robinson, R A S; Lange, M B; Sultana, R et al. (2011) Differential expression and redox proteomics analyses of an Alzheimer disease transgenic mouse model: effects of the amyloid-? peptide of amyloid precursor protein. Neuroscience 177:207-22

Poksay, Karen S; Madden, David T; Peter, Anna K et al. (2011) Valosin-containing protein gene mutations: cellular phenotypes relevant to neurodegeneration. J Mol Neurosci 44:91-102

Zhang, Junli; Rao, Rammohan V; Spilman, Patricia et al. (2011) Endogenously EGFP-Labeled Mouse Embryonic Stem Cells. Aging Dis 2:18-29

Butterfield, D Allan; Galvan, Veronica; Lange, Miranda Bader et al. (2010) In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP. Free Radic Biol Med 48:136-44

Chinta, Shankar J; Poksay, Karen S; Kaundinya, Gaayatri et al. (2009) Endoplasmic reticulum stress-induced cell death in dopaminergic cells: effect of resveratrol. J Mol Neurosci 39:157-68