Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS039006-03
Application #
6394191
Study Section
Special Emphasis Panel (ZRG1-BDCN-3 (01))
Program Officer
Sheehy, Paul A
Project Start
1999-09-30
Project End
2004-06-30
Budget Start
2001-07-01
Budget End
2004-06-30
Support Year
3
Fiscal Year
2001
Total Cost
$212,616
Indirect Cost

  Institution

Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105

  Publications

Zigmond, Michael J; Smeyne, Richard J (2014) Exercise: is it a neuroprotective and if so, how does it work? Parkinsonism Relat Disord 20 Suppl 1:S123-7
Pattarini, R; Rong, Y; Shepherd, K R et al. (2012) Long-lasting transcriptional refractoriness triggered by a single exposure to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine. Neuroscience 214:84-105
Gerecke, Kim M; Jiao, Yun; Pagala, Viswajeeth et al. (2012) Exercise does not protect against MPTP-induced neurotoxicity in BDNF haploinsufficient mice. PLoS One 7:e43250
Korff, Ane; Pfeiffer, Brenda; Smeyne, Michelle et al. (2011) Alterations in glutathione S-transferase pi expression following exposure to MPP+ -induced oxidative stress in the blood of Parkinson's disease patients. Parkinsonism Relat Disord 17:765-8
Gerecke, Kimberly M; Jiao, Yun; Pani, Amar et al. (2010) Exercise protects against MPTP-induced neurotoxicity in mice. Brain Res 1341:72-83
Chen, Pei-Chun; Vargas, Marcelo R; Pani, Amar K et al. (2009) Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte. Proc Natl Acad Sci U S A 106:2933-8
Baquet, Z C; Williams, D; Brody, J et al. (2009) A comparison of model-based (2D) and design-based (3D) stereological methods for estimating cell number in the substantia nigra pars compacta (SNpc) of the C57BL/6J mouse. Neuroscience 161:1082-90
Boyd, Justin D; Jang, Haeman; Shepherd, Kennie R et al. (2007) Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta. Brain Res 1175:107-16
Smeyne, Michelle; Boyd, Justin; Raviie Shepherd, Kennie et al. (2007) GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism. Proc Natl Acad Sci U S A 104:1977-82
Faherty, Ciaran J; Raviie Shepherd, Kennie; Herasimtschuk, Anna et al. (2005) Environmental enrichment in adulthood eliminates neuronal death in experimental Parkinsonism. Brain Res Mol Brain Res 134:170-9

Showing the most recent 10 out of 13 publications