Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS044765-02
Application #
6697251
Study Section
Special Emphasis Panel (ZRG1-MDCN-2 (03))
Program Officer
Jacobs, Tom P
Project Start
2003-01-15
Project End
2006-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$301,982
Indirect Cost

  Institution

Name
University of Florida
Department
Miscellaneous
Type
Schools of Pharmacy
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611

  Publications

Prokai, Laszlo; Nguyen, Vien; Szarka, Szabolcs et al. (2015) The prodrug DHED selectively delivers 17?-estradiol to the brain for treating estrogen-responsive disorders. Sci Transl Med 7:297ra113
Prokai-Tatrai, Katalin; Prokai, Laszlo; Simpkins, James W et al. (2009) Phenolic compounds protect cultured hippocampal neurons against ethanol-withdrawal induced oxidative stress. Int J Mol Sci 10:1773-87
Prokai, Laszlo; Stevens Jr, Stanley M; Rauniyar, Navin et al. (2009) Rapid label-free identification of estrogen-induced differential protein expression in vivo from mouse brain and uterine tissue. J Proteome Res 8:3862-71
Nguyen, V; Bonds, D V; Prokai, L (2008) Measurement of Hydroxyl-Radical Formation in the Rat Striatum by In Vivo Microdialysis and GC-MS. Chromatographia 68:s57-s62
Prokai-Tatrai, Katalin; Perjesi, Pal; Rivera-Portalatin, Nilka M et al. (2008) Mechanistic investigations on the antioxidant action of a neuroprotective estrogen derivative. Steroids 73:280-8
Prokai, Laszlo; Simpkins, James W (2007) Structure-nongenomic neuroprotection relationship of estrogens and estrogen-derived compounds. Pharmacol Ther 114:1-12
Rivera-Portalatin, Nilka M; Vera-Serrano, Jose L; Prokai-Tatrai, Katalin et al. (2007) Comparison of estrogen-derived ortho-quinone and para-quinol concerning induction of oxidative stress. J Steroid Biochem Mol Biol 105:71-5
Prokai, Laszlo; Zharikova, Alevtina D; Stevens Jr, Stanley M (2005) Effect of chronic morphine exposure on the synaptic plasma-membrane subproteome of rats: a quantitative protein profiling study based on isotope-coded affinity tags and liquid chromatography/mass spectrometry. J Mass Spectrom 40:169-75
Prokai-Tatrai, Katalin; Prokai, Laszlo (2005) Impact of metabolism on the safety of estrogen therapy. Ann N Y Acad Sci 1052:243-57
Simpkins, James W; Wang, Jian; Wang, Xiaofei et al. (2005) Mitochondria play a central role in estrogen-induced neuroprotection. Curr Drug Targets CNS Neurol Disord 4:69-83

Showing the most recent 10 out of 13 publications