Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS045187-02
Application #
6688330
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Program Officer
Nunn, Michael
Project Start
2002-12-15
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$396,625
Indirect Cost
Name
Rockefeller University
Department
Microbiology/Immun/Virology
Type
Other Domestic Higher Education
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065
Hess, Samuel; Rambukkana, Anura (2015) Bacterial-induced cell reprogramming to stem cell-like cells: new premise in host-pathogen interactions. Curr Opin Microbiol 23:179-88
Masaki, Toshihiro; Qu, Jinrong; Cholewa-Waclaw, Justyna et al. (2013) Reprogramming adult Schwann cells to stem cell-like cells by leprosy bacilli promotes dissemination of infection. Cell 152:51-67
Im, Jin S; Tapinos, Nikos; Chae, Gue-Tae et al. (2006) Expression of CD1d molecules by human schwann cells and potential interactions with immunoregulatory invariant NK T cells. J Immunol 177:5226-35
Tapinos, Nikos; Ohnishi, Makoto; Rambukkana, Anura (2006) ErbB2 receptor tyrosine kinase signaling mediates early demyelination induced by leprosy bacilli. Nat Med 12:961-6
Tapinos, Nikos; Rambukkana, Anura (2005) Insights into regulation of human Schwann cell proliferation by Erk1/2 via a MEK-independent and p56Lck-dependent pathway from leprosy bacilli. Proc Natl Acad Sci U S A 102:9188-93
Rambukkana, Anura (2004) Mycobacterium leprae-induced demyelination: a model for early nerve degeneration. Curr Opin Immunol 16:511-8
Rambukkana, Anura; Kunz, Stefan; Min, Jenny et al. (2003) Targeting Schwann cells by nonlytic arenaviral infection selectively inhibits myelination. Proc Natl Acad Sci U S A 100:16071-6