Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
1R01NS064256-01A1
Application #
7729103
Study Section
Neurotransporters, Receptors, and Calcium Signaling Study Section (NTRC)
Program Officer
Hicks, Ramona R
Project Start
2009-07-16
Project End
2011-06-30
Budget Start
2009-07-16
Budget End
2010-06-30
Support Year
1
Fiscal Year
2009
Total Cost
$375,000
Indirect Cost
Name
University of Kansas
Department
Physiology
Type
Schools of Medicine
DUNS #
016060860
City
Kansas City
State
KS
Country
United States
Zip Code
66160
Belousov, Andrei B; Fontes, Joseph D (2014) Neuronal gap junction coupling as the primary determinant of the extent of glutamate-mediated excitotoxicity. J Neural Transm (Vienna) 121:837-46
Belousov, Andrei B; Fontes, Joseph D (2013) Neuronal gap junctions: making and breaking connections during development and injury. Trends Neurosci 36:227-36
Belousov, Andrei B (2012) Novel model for the mechanisms of glutamate-dependent excitotoxicity: role of neuronal gap junctions. Brain Res 1487:123-30
Wang, Yongfu; Song, Ji-Hoon; Denisova, Janna V et al. (2012) Neuronal gap junction coupling is regulated by glutamate and plays critical role in cell death during neuronal injury. J Neurosci 32:713-25
Belousov, Andrei B (2012) The regulation and role of neuronal gap junctions during neuronal injury. Channels (Austin) 6:390-2
Belousov, Andrei B; Wang, Yongfu; Song, Ji-Hoon et al. (2012) Neuronal gap junctions play a role in the secondary neuronal death following controlled cortical impact. Neurosci Lett 524:16-9
Song, Ji-Hoon; Wang, Yongfu; Fontes, Joseph D et al. (2012) Regulation of connexin 36 expression during development. Neurosci Lett 513:17-9
Park, Won-Mee; Wang, Yongfu; Park, Soodong et al. (2011) Interplay of chemical neurotransmitters regulates developmental increase in electrical synapses. J Neurosci 31:5909-20
Wang, Yongfu; Belousov, Andrei B (2011) Deletion of neuronal gap junction protein connexin 36 impairs hippocampal LTP. Neurosci Lett 502:30-2
Michaelis, E K; Wang, X; Pal, R et al. (2011) Neuronal Glud1 (glutamate dehydrogenase 1) over-expressing mice: increased glutamate formation and synaptic release, loss of synaptic activity, and adaptive changes in genomic expression. Neurochem Int 59:473-81

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