The goal of this collaborative project is to develop an automated hand-held micromachined electrochemical flow analyzer for high-speed single-cell genomics analysis. Innovative biosensor technology, based on new highly selective and sensitive PNA-dendrimer recognition chemistry, high-density parallel-channel hybridization microreactors, a label-free electrochemical detection of the released targets at downstream microelectrodes, and state-of-the-art microfabrication/micromachining technology will be used for meeting the challenges of rapid and sensitive single-cell nucleic-acid sequencing.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Project (R01)
Project #
1R01RR014549-01
Application #
6039889
Study Section
Special Emphasis Panel (ZRR1-BT-4 (01))
Program Officer
Schloss, Jeffery
Project Start
1999-09-28
Project End
2001-08-31
Budget Start
1999-09-28
Budget End
2000-08-31
Support Year
1
Fiscal Year
1999
Total Cost
Indirect Cost
Name
New Mexico State University Las Cruces
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
City
Las Cruces
State
NM
Country
United States
Zip Code
88003
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