): The investigator plans to prospectively evaluate 50 children with a clinical diagnosis of obstructive sleep apnea syndrome (OSAS) by a standardized history, physical examination, review of a tape recording of breathing during sleep, lateral neck radiograph to assess adenoid size, EKG to assess right ventricular hypertrophy, and behavioral assessment. A clinical assessment score will be assigned to each patient. Nocturnal polysomnography (NPSG) will then be used as the gold reference standard to determine the presence or absence of true sleep apnea. Children with a positive NPSG will undergo tonsillectomy and adenoidectomy. Children with negative NPSG will be randomized to undergo tonsillectomy and adenoidectomy or no surgery. All children will be reassessed in an identical fashion with follow-up NPSGs six months later.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Small Research Grants (R03)
Project #
1R03HD037386-01
Application #
2807393
Study Section
Pediatrics Subcommittee (CHHD)
Project Start
1998-07-01
Project End
2000-06-30
Budget Start
1998-07-01
Budget End
1999-06-30
Support Year
1
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Suny Downstate Medical Center
Department
Otolaryngology
Type
Schools of Medicine
DUNS #
068552207
City
Brooklyn
State
NY
Country
United States
Zip Code
11203
Goldstein, Nira A; Pugazhendhi, Vasanthi; Rao, Sudha M et al. (2004) Clinical assessment of pediatric obstructive sleep apnea. Pediatrics 114:33-43