Increased life expectancies create a need for greater financial decision making on the part of individuals. Yet little research has examined how financial decision making changes over the course of the lifespan. We propose to investigate behavioral and neural responses during anticipation of financial reward and risk in young, middle-aged, and old samples. We will also examine the influence of incidental affective cues and cognitive load on financial risk taking in these groups. The proposed studies are guided by a neuroeconomic model of how anticipatory affect can influence financial risk taking. Findings promise to elucidate not only how the brain anticipates reward and risk, but also how this may change with age. ? ? Since people are living longer than ever before, they must increasingly make important decisions about their financial future -- yet little research has examined financial risk- taking, or how this behavior changes with age. We propose to use cutting edge brain imaging technology to examine predictors of financial risk taking in young, middle-aged, and older adults. The findings promise to illuminate how individuals make both optimal and suboptimal financial decisions over the course of the lifespan. ? ? ?

National Institute of Health (NIH)
National Institute on Aging (NIA)
Exploratory/Developmental Grants (R21)
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Special Emphasis Panel (ZAG1-ZIJ-1 (M1))
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Patmios, Georgeanne E
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Stanford University
Schools of Arts and Sciences
United States
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Samanez-Larkin, Gregory R; Knutson, Brian (2015) Decision making in the ageing brain: changes in affective and motivational circuits. Nat Rev Neurosci 16:278-89
Samanez-Larkin, Gregory R; Worthy, Darrell A; Mata, Rui et al. (2014) Adult age differences in frontostriatal representation of prediction error but not reward outcome. Cogn Affect Behav Neurosci 14:672-82
Wu, Charlene C; Samanez-Larkin, Gregory R; Katovich, Kiefer et al. (2014) Affective traits link to reliable neural markers of incentive anticipation. Neuroimage 84:279-89
Benetos, Athanase; Kark, Jeremy D; Susser, Ezra et al. (2013) Tracking and fixed ranking of leukocyte telomere length across the adult life course. Aging Cell 12:615-21
Kuhnen, Camelia M; Samanez-Larkin, Gregory R; Knutson, Brian (2013) Serotonergic genotypes, neuroticism, and financial choices. PLoS One 8:e54632
Sacchet, Matthew D; Knutson, Brian (2013) Spatial smoothing systematically biases the localization of reward-related brain activity. Neuroimage 66:270-7
Samanez-Larkin, Gregory R; Levens, Sara M; Perry, Lee M et al. (2012) Frontostriatal white matter integrity mediates adult age differences in probabilistic reward learning. J Neurosci 32:5333-7
Samanez-Larkin, Gregory R; Wagner, Anthony D; Knutson, Brian (2011) Expected value information improves financial risk taking across the adult life span. Soc Cogn Affect Neurosci 6:207-17
Knutson, Brian; Samanez-Larkin, Gregory R; Kuhnen, Camelia M (2011) Gain and loss learning differentially contribute to life financial outcomes. PLoS One 6:e24390
Samanez-Larkin, Gregory R; Kuhnen, Camelia M; Yoo, Daniel J et al. (2010) Variability in nucleus accumbens activity mediates age-related suboptimal financial risk taking. J Neurosci 30:1426-34

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