The proposed project stands to improve understanding of the role of impulsive behavior in adolescent cigarette-smoking uptake. The primary goal of this research is to cross-sectionally identify relations between two primary dimensions of impulsive behavior (i.e., inhibitory-control and delay-of-reward impulsive behaviors) as assessed by laboratory-task procedures at the different stages to becoming an adolescent smoker. The proposed study is largely correlational; however, this study is expected to generate preliminary data for future longitudinal research aimed at more firmly establishing causal or consequent relations between impulsivity and adolescent cigarette-smoking. Additionally, this study should help clarify the specific behavioral mechanisms related to adolescent smoking that will later serve as additional points of emphasis for adolescent smoking prevention and cessation efforts, with relations identified at earlier smoking stages informing prevention efforts, and at later stages, cessation efforts. The use of laboratory procedures also has the added benefit of increased sensitivity to detection of temporary increases in impulsive behavior. Such increases in impulsivity may occur as a result of certain environmental events and may play a determining role at different stages of smoking uptake. For example, pilot data using a laboratory procedure suggest a period of heightened impulsivity associated with adolescents trying cigarettes for the first time (Reynolds et al., 2003). Related to this, a secondary feature of the proposed project will involve exploring relations between self-reported negative life events and impulsive behavior at the different smoking stages. These stress-related variables are already recognized risk factors to smoking initiation among adolescents. This population may be particularly sensitive to negative life events, and these may increase vulnerability to trying cigarettes or the escalation to more frequent use, either in their own right or indirectly through the effects of stress on impulsivity. The possible role of impulsive behavior as a mediator between negative life events and cigarette-smoking status among adolescents will be explored. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21DA020423-01A1
Application #
7099379
Study Section
Biobehavioral Regulation, Learning and Ethology Study Section (BRLE)
Program Officer
Lynch, Minda
Project Start
2006-06-01
Project End
2008-05-31
Budget Start
2006-06-01
Budget End
2007-05-31
Support Year
1
Fiscal Year
2006
Total Cost
$211,320
Indirect Cost
Name
Nationwide Children's Hospital
Department
Type
DUNS #
147212963
City
Columbus
State
OH
Country
United States
Zip Code
43205
Reynolds, Brady; Fields, Sherecce (2012) Delay discounting by adolescents experimenting with cigarette smoking. Addiction 107:417-24
Fields, Sherecce; Collins, Christine; Leraas, Kristen et al. (2009) Dimensions of impulsive behavior in adolescent smokers and nonsmokers. Exp Clin Psychopharmacol 17:302-11
Fields, Sherecce; Leraas, Kristen; Collins, Christine et al. (2009) Delay discounting as a mediator of the relationship between perceived stress and cigarette smoking status in adolescents. Behav Pharmacol 20:455-60
Reynolds, Brady; Penfold, Robert B; Patak, Michele (2008) Dimensions of impulsive behavior in adolescents: laboratory behavioral assessments. Exp Clin Psychopharmacol 16:124-31
Reynolds, Brady; Patak, Michele; Shroff, Palak (2007) Adolescent smokers rate delayed rewards as less certain than adolescent nonsmokers. Drug Alcohol Depend 90:301-3
Reynolds, Brady; Patak, Michele; Shroff, Palak et al. (2007) Laboratory and self-report assessments of impulsive behavior in adolescent daily smokers and nonsmokers. Exp Clin Psychopharmacol 15:264-71
Reynolds, Brady (2006) A review of delay-discounting research with humans: relations to drug use and gambling. Behav Pharmacol 17:651-67