This R21 proposal proposes to systematically sequence 10,000 human adipose expressed sequence tags (ESTs) to 1) obtain a global view of normal adipocyte gene expression, 2) discover novel fat specific or fat abundant genes, and 3) find new functions of known genes and fat tissue.
Yang, Rong-Ze; Lee, Mi-Jeong; Hu, Hong et al. (2006) Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action. Am J Physiol Endocrinol Metab 290:E1253-61 |
Yang, Rong-Ze; Lee, Mi-Jeong; Hu, Hong et al. (2006) Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications. PLoS Med 3:e287 |
Yang, Rong-Ze; Huang, Qing; Xu, Aihua et al. (2003) Comparative studies of resistin expression and phylogenomics in human and mouse. Biochem Biophys Res Commun 310:927-35 |
Yang, Rong-Ze; Blaileanu, Greorghe; Hansen, Barbara C et al. (2002) cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase. Genomics 79:445-50 |