This is an R21 application to develop an innovative approach to characterize and quantify diabetic sympathetic neuropathy and its effect on microvascular tone. The authors claim a unique approach, which will help to identify how diabetes mellitus affects sympathetic and microvascular function.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21NS038846-01
Application #
2759020
Study Section
Special Emphasis Panel (ZRG2-NMS (03))
Program Officer
Nichols, Paul L
Project Start
1998-09-30
Project End
2000-08-31
Budget Start
1998-09-30
Budget End
1999-08-31
Support Year
1
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Iowa
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
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Corbit, Kevin C; Trakul, Nicholas; Eves, Eva M et al. (2003) Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein. J Biol Chem 278:13061-8
Agapitov, Alexei V; Correia, Marcelo L G; Sinkey, Christine A et al. (2002) Impaired skeletal muscle and skin microcirculatory function in human obesity. J Hypertens 20:1401-5