Abstract

This is an R21 application to develop an innovative approach to characterize and quantify diabetic sympathetic neuropathy and its effect on microvascular tone. The authors claim a unique approach, which will help to identify how diabetes mellitus affects sympathetic and microvascular function.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21NS038846-02
Application #
2892483
Study Section
Special Emphasis Panel (ZRG2-NMS (03))
Program Officer
Nichols, Paul L
Project Start
1998-09-30
Project End
2000-08-31
Budget Start
1999-09-01
Budget End
2000-08-31
Support Year
2
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
University of Iowa
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242

  Publications

Zhou, Limei; Li, Jing; Goldsmith, Adam M et al. (2004) Human bronchial smooth muscle cell lines show a hypertrophic phenotype typical of severe asthma. Am J Respir Crit Care Med 169:703-11
Corbit, Kevin C; Trakul, Nicholas; Eves, Eva M et al. (2003) Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein. J Biol Chem 278:13061-8
Agapitov, Alexei V; Correia, Marcelo L G; Sinkey, Christine A et al. (2002) Impaired skeletal muscle and skin microcirculatory function in human obesity. J Hypertens 20:1401-5