Studies are underway of the digestibility and utilization of the protein and energy of oats when providing 22 to 66% of calories in diet of infants. During prolonged feeding at the highest levels, the absorption of trace minerals will be studied: Zn, Fe, Cu, Mg, Ca and PO4, possibly Mn, Cr, and others. The ability of wheat-legume and rice-legume mixtures to satisfy the protein needs of infants, and their effects on mineral absorption are being studied. Protein requirements of convalescent malnourished infants (6-11.9 months) and small children (12-33 months) are being determined with a 60-40 whey-casein formula at 8.0, 6.7 and 5.5% protein calories for the younger group, and at 6.4 and 4.7% for the older group. Adequacy is judged by anthropometry, standard biochemical indices, and body composition by H218O and bromide dilutions for total body water and extracellular water estimations, respectively.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Unknown (R22)
Project #
5R22HD010111-08
Application #
3445098
Study Section
Nutrition Study Section (NTN)
Project Start
1979-09-29
Project End
1987-08-31
Budget Start
1985-09-01
Budget End
1986-08-31
Support Year
8
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Graham, G G; MacLean Jr, W C; Brown, K H et al. (1996) Protein requirements of infants and children: growth during recovery from malnutrition. Pediatrics 97:499-505
Graham, G G (1993) Quality-protein maize with a high fat content as a weaning food. J Pediatr Gastroenterol Nutr 17:139-44
Graham, G G; Lembcke, J; Morales, E (1990) Quality-protein maize as the sole source of dietary protein and fat for rapidly growing young children. Pediatrics 85:85-91
Graham, G G; MacLean Jr, W C; Morales, E (1990) The nutritional value of oat flour for very young children. J Pediatr Gastroenterol Nutr 10:344-50
Graham, G G; MacLean Jr, W C; Morales, E et al. (1986) Digestibility and utilization of protein and energy from Nasha, a traditional Sudanese fermented sorghum weaning food. J Nutr 116:978-84