Abstract

Cancer incidence, morbidity and mortality in the Commonwealth of Kentucky are among the highest in the nation. The James Graham Brown Cancer Center's mission is to reduce cancer incidence, morbidity and mortality particularly within the Commonwealth and the region we serve. The clinical and research programs of the James Graham Brown Cancer Center have experienced tremendous growth in faculty recruitment, and in the development of scientific and clinical programs and shared use facilities. The long-term objective of the University of Louisville Cancer Education Program is to recruit, educate and motivate outstanding undergraduate and professional students to pursue further training and future careers in cancer research. The program fits exceptionally well within the strategic plans of the University of Louisville and we will implement novel recruitment, evaluation, and dissemination strategies to achieve the objectives of the program.

Public Health Relevance

Cancer incidence, morbidity and mortality in the Commonwealth of Kentucky are among the highest in the nation. The James Graham Brown Cancer Center's mission is to reduce cancer incidence, morbidity and mortality particularly within the Commonwealth and the region we serve. The clinical and research programs of the James Graham Brown Cancer Center have experienced tremendous growth in faculty recruitment, and in the development of scientific and clinical programs and shared use facilities. The long-term objective of the University of Louisville Cancer Education Program is to recruit, educate and motivate outstanding undergraduate and professional students to pursue further training and future careers in cancer research.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Education Projects (R25)
Project #
5R25CA134283-03
Application #
8540828
Study Section
Subcommittee G - Education (NCI)
Program Officer
Korczak, Jeannette F
Project Start
2011-09-14
Project End
2016-08-31
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
3
Fiscal Year
2013
Total Cost
$296,645
Indirect Cost
$21,974

  Institution

Name
University of Louisville
Department
Pharmacology
Type
Schools of Medicine
DUNS #
057588857
City
Louisville
State
KY
Country
United States
Zip Code
40292

  Publications

Bardi, Gina T; Smith, Mary Ann; Hood, Joshua L (2018) Melanoma exosomes promote mixed M1 and M2 macrophage polarization. Cytokine 105:63-72
Heitz, Adaline E; Baumgartner, Richard N; Baumgartner, Kathy B et al. (2018) Healthy lifestyle impact on breast cancer-specific and all-cause mortality. Breast Cancer Res Treat 167:171-181
Neely, Aaron M; Zhao, Guoping; Schwarzer, Christian et al. (2018) N-(3-Oxo-acyl)-homoserine lactone induces apoptosis primarily through a mitochondrial pathway in fibroblasts. Cell Microbiol 20:
Zimmaro, Lauren A; Sephton, Sandra E; Siwik, Chelsea J et al. (2018) Depressive symptoms predict head and neck cancer survival: Examining plausible behavioral and biological pathways. Cancer 124:1053-1060
Garza-Morales, Rodolfo; Yaddanapudi, Kavitha; Perez-Hernandez, Rigoberto et al. (2018) Temozolomide renders murine cancer cells susceptible to oncolytic adenovirus replication and oncolysis. Cancer Biol Ther 19:188-197
Hein, David W; Kidd, La Creis R (2018) Design and Success of a 21st Century Cancer Education Program at the University of Louisville. J Cancer Educ 33:298-308
Hein, David W; Fakis, Giannoulis; Boukouvala, Sotiria (2018) Functional expression of human arylamine N-acetyltransferase NAT1*10 and NAT1*11 alleles: a mini review. Pharmacogenet Genomics 28:238-244
Carlisle, Samantha M; Trainor, Patrick J; Doll, Mark A et al. (2018) Knockout of human arylamine N-acetyltransferase 1 (NAT1) in MDA-MB-231 breast cancer cells leads to increased reserve capacity, maximum mitochondrial capacity, and glycolytic reserve capacity. Mol Carcinog 57:1458-1466
Xiao, Jingjing; Egger, Michael E; McMasters, Kelly M et al. (2018) Differential expression of ABCB5 in BRAF inhibitor-resistant melanoma cell lines. BMC Cancer 18:675
Samykutty, Abhilash; Grizzle, William E; Fouts, Benjamin L et al. (2018) Optoacoustic imaging identifies ovarian cancer using a microenvironment targeted theranostic wormhole mesoporous silica nanoparticle. Biomaterials 182:114-126

Showing the most recent 10 out of 43 publications