Charged with the responsibility of educating future health professionals and scientists, the University of Texas Health Science Center at San Antonio (UTHSCSA) has enthusiastically embraced this mission, training the second highest percentage of Hispanic physicians in the country and providing a steady stream of scientists and health professionals to South Texas and the nation. Historically however, less than 15% of doctoral students in the Graduate School of Biomedical Sciences (GSBS) are from underrepresented minority (URM) groups. In a recent review of the Graduate School's achievements, the leadership recognized a disparity between the school's role in the institutional mission of educating a diverse student body and its measurable outcomes. It became evident that if the GSBS hoped to realize its vision of training the next generation of talented and diverse scientific innovators and accomplish its mission coincident with being a Hispanic serving institution, significant changes were warranted. To pursue this commitment, the GSBS conducted an extensive evaluation of its programs and then designed the series of programs and activities articulated in this proposal to proactively address the problems of recruiting and retaining URM students. Programmatic evaluations uncovered three glaring problems: 1.) the numbers of URM students entering the GSBS was inconsistent with UTHSCSA's institutional designation as a Hispanic serving Institution, 2.) 25% of URM students entering the program leave (dismissed or withdraw) within the first year, and 3.) for those that survive the first year, URM students graduate at a much slower rate than their non URM colleagues. The programmatic changes to be implemented include enrichment courses for first year URM students, individualized mentoring plans to keep students focused, and professional development workshops to prepare students for independent research. Through these initiatives, IMSD students will complete their degrees in a manner consistent within predominant institutional norms for non-URM students. IMSD students will graduate with outstanding publication and research records and as such will be highly recruited by prestigious institutions with T32 support. These initiates will serve the common goal of increasing the number of URM students who enter the professorate and begin to address the significant disparity of URM in the STEM.

Public Health Relevance

This proposal seeks to enhance the training of underrepresented minority students pursuing their doctoral degrees in biomedical research. These students will potentially interact with the corresponding minority communities to address major issues related to health care. For example, we anticipate training Hispanic students who could address issues relating to diabetes, stroke and obesity, all which occur at high rates in the Hispanic community.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Education Projects (R25)
Project #
5R25GM095480-03
Application #
8520335
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Janes, Daniel E
Project Start
2011-08-01
Project End
2016-07-31
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
3
Fiscal Year
2013
Total Cost
$287,238
Indirect Cost
$21,277
Name
University of Texas Health Science Center San Antonio
Department
Type
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Robles, Andrew J; McCowen, Shelby; Cai, Shengxin et al. (2017) Structure-Activity Relationships of New Natural Product-Based Diaryloxazoles with Selective Activity against Androgen Receptor-Positive Breast Cancer Cells. J Med Chem 60:9275-9289
Aguilar, David D; Giuffrida, Andrea; Lodge, Daniel J (2016) THC and endocannabinoids differentially regulate neuronal activity in the prefrontal cortex and hippocampus in the subchronic PCP model of schizophrenia. J Psychopharmacol 30:169-81
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Robles, Andrew J; Du, Lin; Cichewicz, Robert H et al. (2016) Maximiscin Induces DNA Damage, Activates DNA Damage Response Pathways, and Has Selective Cytotoxic Activity against a Subtype of Triple-Negative Breast Cancer. J Nat Prod 79:1822-7
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González-Juarbe, Norberto; Gilley, Ryan Paul; Hinojosa, Cecilia Anahí et al. (2015) Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia. PLoS Pathog 11:e1005337
Ullevig, Sarah L; Kim, Hong Seok; Nguyen, Huynh Nga et al. (2014) Ursolic acid protects monocytes against metabolic stress-induced priming and dysfunction by preventing the induction of Nox4. Redox Biol 2:259-66
Aguilar, David D; Chen, Li; Lodge, Daniel J (2014) Increasing endocannabinoid levels in the ventral pallidum restore aberrant dopamine neuron activity in the subchronic PCP rodent model of schizophrenia. Int J Neuropsychopharmacol 18:
Rodriguez, Jesse S; Cunningham, Colin S; Moura, Fernando B et al. (2014) Discriminative stimulus and hypothermic effects of some derivatives of the nAChR agonist epibatidine in mice. Psychopharmacology (Berl) 231:4455-66
Du, Lin; Robles, Andrew J; King, Jarrod B et al. (2014) Crowdsourcing natural products discovery to access uncharted dimensions of fungal metabolite diversity. Angew Chem Int Ed Engl 53:804-9

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