Having improved the recruitment and retention rates of underrepresented (UR) students in the graduate program at the University of Texas Health Science Center San Antonio (UTHSCSA), we now shift our we now focus our attention on the development of novel and cutting edge practices and processes that will produce UR students that are not only highly competitive, but are leaders, in the biomedical workforce. Here we propose a series of systematic interventions designed to sharpen critical thinking skills and develop grant and manuscript writing as well as presentation skills. Successful integration of these strategies will prepare IMSD scholars for the most competitive positions in the biomedical workforce.

Public Health Relevance

This proposal seeks to enhance the training of underrepresented minority student pursuing their doctoral degrees in biomedical research. These students will potentially interact with the corresponding minority communities to address major issues related to health care. For example, we anticipate training Hispanic students who could address issues relating to diabetes, stroke and obesity, all which occurs at high rates in the Hispanic community.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Education Projects (R25)
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NIGMS Initial Review Group (TWD)
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Koduri, Sailaja
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University of Texas Health Science Center
Graduate Schools
San Antonio
United States
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Robles, Andrew J; McCowen, Shelby; Cai, Shengxin et al. (2017) Structure-Activity Relationships of New Natural Product-Based Diaryloxazoles with Selective Activity against Androgen Receptor-Positive Breast Cancer Cells. J Med Chem 60:9275-9289
Aguilar, David D; Giuffrida, Andrea; Lodge, Daniel J (2016) THC and endocannabinoids differentially regulate neuronal activity in the prefrontal cortex and hippocampus in the subchronic PCP model of schizophrenia. J Psychopharmacol 30:169-81
Robles, Andrew J; Cai, Shengxin; Cichewicz, Robert H et al. (2016) Selective activity of deguelin identifies therapeutic targets for androgen receptor-positive breast cancer. Breast Cancer Res Treat 157:475-88
Robles, Andrew J; Du, Lin; Cichewicz, Robert H et al. (2016) Maximiscin Induces DNA Damage, Activates DNA Damage Response Pathways, and Has Selective Cytotoxic Activity against a Subtype of Triple-Negative Breast Cancer. J Nat Prod 79:1822-7
Robles, Andrew J; Peng, Jiangnan; Hartley, Rachel M et al. (2015) Melampodium leucanthum, a source of cytotoxic sesquiterpenes with antimitotic activities. J Nat Prod 78:388-95
González-Juarbe, Norberto; Gilley, Ryan Paul; Hinojosa, Cecilia Anahí et al. (2015) Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia. PLoS Pathog 11:e1005337
Du, Lin; Robles, Andrew J; King, Jarrod B et al. (2014) Crowdsourcing natural products discovery to access uncharted dimensions of fungal metabolite diversity. Angew Chem Int Ed Engl 53:804-9
Ullevig, Sarah L; Kim, Hong Seok; Nguyen, Huynh Nga et al. (2014) Ursolic acid protects monocytes against metabolic stress-induced priming and dysfunction by preventing the induction of Nox4. Redox Biol 2:259-66
Aguilar, David D; Chen, Li; Lodge, Daniel J (2014) Increasing endocannabinoid levels in the ventral pallidum restore aberrant dopamine neuron activity in the subchronic PCP rodent model of schizophrenia. Int J Neuropsychopharmacol 18:
Rodriguez, Jesse S; Cunningham, Colin S; Moura, Fernando B et al. (2014) Discriminative stimulus and hypothermic effects of some derivatives of the nAChR agonist epibatidine in mice. Psychopharmacology (Berl) 231:4455-66

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