This proposal describes a Post-baccalaureate Research Education Program (PREP) at Yale University that will provide eight URM baccalaureate graduates with a one-year program of faculty-mentored research training in the biomedical sciences and educational preparation for graduate school admission. The long-term goal of the proposed Yale PREP is to increase the number of underrepresented minority (URM) students pursuing doctoral studies in the biomedical sciences, especially at Yale. Yale PREP will recruit baccalaureate graduates from a wide range of colleges and universities but especially historically black colleges and universities, Hispanic serving institutions, and the University of Puerto Rico, as well as through an exciting new partnership between Yale and Chaminade University of Honolulu, a Native Hawaiian and Pacific Islander serving institution. The goal of Yale PREP is to provide program participants with a foundation of knowledge, experiences, and skills necessary to be successful graduate students. Specific objectives for program participants are: 1) To experience life as a biomedical graduate student at a major research university, taking courses and receiving mentoring alongside first year PhD students. 2) To conduct, under supervision of a faculty mentor, an independent research project for which they ultimately take responsibility for planning and executing experiments, including formulating and testing hypotheses. 3) To study an educational curriculum that consists of GRE preparation, graduate school and career workshops, a research literature seminar course, a journal club covering health-disparities research, Yale courses, and research presentations. Program participants will devote 75% of their time to independent research and 25% to the educational curriculum. Expected outcomes for Yale PREP participants include improved laboratory skills, problem-solving abilities, biomedical research knowledge, and presentation skills. They will also demonstrate an increased commitment to biomedical research, which should ultimately culminate in the pursuit of the PhD degree. The impact of the proposed Yale PREP will be to expand the pool of exceptional doctoral students from underrepresented groups in the biomedical sciences and thus the diversity of perspectives needed to address important problems in human health and disease, including health disparities.

Public Health Relevance

Yale University proposes to establish a Post-baccalaureate Research Education Program (PREP) that will provide underrepresented minority baccalaureate graduates with faculty-mentored research training in the biomedical sciences and educational preparation for graduate school admission. The ultimate goal is to expand the pool of exceptional doctoral students from underrepresented groups in the biomedical sciences and the diversity of perspectives needed to address important problems in human health and disease, including health disparities.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Education Projects (R25)
Project #
5R25GM104553-04
Application #
9232166
Study Section
Training and Workforce Development Subcommittee - D (TWD-D)
Program Officer
Gibbs, Kenneth D
Project Start
2014-05-01
Project End
2018-02-28
Budget Start
2017-03-01
Budget End
2018-02-28
Support Year
4
Fiscal Year
2017
Total Cost
$308,558
Indirect Cost
$19,216
Name
Yale University
Department
Type
Schools of Arts and Sciences
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Greiling, Teri M; Dehner, Carina; Chen, Xinguo et al. (2018) Commensal orthologs of the human autoantigen Ro60 as triggers of autoimmunity in lupus. Sci Transl Med 10:
Wickham, Robert J; Nunes, Eric J; Hughley, Shannon et al. (2018) Evaluating oral flavorant effects on nicotine self-administration behavior and phasic dopamine signaling. Neuropharmacology 128:33-42
Addy, Nii A; Nunes, Eric J; Hughley, Shannon M et al. (2018) The L-type calcium channel blocker, isradipine, attenuates cue-induced cocaine-seeking by enhancing dopaminergic activity in the ventral tegmental area to nucleus accumbens pathway. Neuropsychopharmacology 43:2361-2372
Small, Keri M; Nunes, Eric; Hughley, Shannon et al. (2016) Ventral tegmental area muscarinic receptors modulate depression and anxiety-related behaviors in rats. Neurosci Lett 616:80-5