Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI035177-03
Application #
2070639
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1994-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Huigens 3rd, Robert W; Ma, Luyan; Gambino, Christopher et al. (2008) Control of bacterial biofilms with marine alkaloid derivatives. Mol Biosyst 4:614-21
Baynham, Patricia J; Ramsey, Deborah M; Gvozdyev, Borys V et al. (2006) The Pseudomonas aeruginosa ribbon-helix-helix DNA-binding protein AlgZ (AmrZ) controls twitching motility and biogenesis of type IV pili. J Bacteriol 188:132-40
Tart, Anne H; Wolfgang, Matthew C; Wozniak, Daniel J (2005) The alternative sigma factor AlgT represses Pseudomonas aeruginosa flagellum biosynthesis by inhibiting expression of fleQ. J Bacteriol 187:7955-62
Ramsey, Deborah M; Wozniak, Daniel J (2005) Understanding the control of Pseudomonas aeruginosa alginate synthesis and the prospects for management of chronic infections in cystic fibrosis. Mol Microbiol 56:309-22
Mishra, Meenu; Parise, Gina; Jackson, Kara D et al. (2005) The BvgAS signal transduction system regulates biofilm development in Bordetella. J Bacteriol 187:1474-84
Ramsey, Deborah M; Baynham, Patricia J; Wozniak, Daniel J (2005) Binding of Pseudomonas aeruginosa AlgZ to sites upstream of the algZ promoter leads to repression of transcription. J Bacteriol 187:4430-43
Jackson, Kara D; Starkey, Melissa; Kremer, Stefanie et al. (2004) Identification of psl, a locus encoding a potential exopolysaccharide that is essential for Pseudomonas aeruginosa PAO1 biofilm formation. J Bacteriol 186:4466-75
Cobb, Laura M; Mychaleckyj, Josyf C; Wozniak, Daniel J et al. (2004) Pseudomonas aeruginosa flagellin and alginate elicit very distinct gene expression patterns in airway epithelial cells: implications for cystic fibrosis disease. J Immunol 173:5659-70
Wozniak, Daniel J; Sprinkle, April B; Baynham, Patricia J (2003) Control of Pseudomonas aeruginosa algZ expression by the alternative sigma factor AlgT. J Bacteriol 185:7297-300
Wozniak, Daniel J; Wyckoff, Timna J O; Starkey, Melissa et al. (2003) Alginate is not a significant component of the extracellular polysaccharide matrix of PA14 and PAO1 Pseudomonas aeruginosa biofilms. Proc Natl Acad Sci U S A 100:7907-12

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