Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI038410-02
Application #
2075450
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1995-09-01
Project End
2000-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
Viswanathan, V K; Kurtz, Sherry; Pedersen, Lisa L et al. (2002) The cytochrome c maturation locus of Legionella pneumophila promotes iron assimilation and intracellular infection and contains a strain-specific insertion sequence element. Infect Immun 70:1842-52
Molmeret, Maelle; Alli, O A Terry; Zink, Steven et al. (2002) icmT is essential for pore formation-mediated egress of Legionella pneumophila from mammalian and protozoan cells. Infect Immun 70:69-78
Pedersen, L L; Radulic, M; Doric, M et al. (2001) HtrA homologue of Legionella pneumophila: an indispensable element for intracellular infection of mammalian but not protozoan cells. Infect Immun 69:2569-79
Gao, L Y; Kwaik, Y A (2000) The modulation of host cell apoptosis by intracellular bacterial pathogens. Trends Microbiol 8:306-13
Gao, L Y; Kwaik, Y A (2000) The mechanism of killing and exiting the protozoan host Acanthamoeba polyphaga by Legionella pneumophila. Environ Microbiol 2:79-90
Gao, L; Abu Kwaik, Y (2000) Hijacking of apoptotic pathwaysby bacterial pathogens. Microbes Infect 2:1705-19
Harb, O S; Abu Kwaik, Y (2000) Essential role for the Legionella pneumophila rep helicase homologue in intracellular infection of mammalian cells. Infect Immun 68:6970-8
Harb, O S; Abu Kwaik, Y (2000) Characterization of a macrophage-specific infectivity locus (milA) of Legionella pneumophila. Infect Immun 68:368-76
Harb, O S; Gao, L Y; Abu Kwaik, Y (2000) From protozoa to mammalian cells: a new paradigm in the life cycle of intracellular bacterial pathogens. Environ Microbiol 2:251-65
Alli, O A; Gao, L Y; Pedersen, L L et al. (2000) Temporal pore formation-mediated egress from macrophages and alveolar epithelial cells by Legionella pneumophila. Infect Immun 68:6431-40

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