Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29CA050780-03
Application #
3459661
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1989-07-01
Project End
1994-06-30
Budget Start
1991-07-01
Budget End
1992-06-30
Support Year
3
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Toloza, E M; Hunt, K; Miller, A R et al. (1997) Transduction of murine and human tumors using recombinant adenovirus vectors. Ann Surg Oncol 4:70-9
Rhoades, K L; Golub, S H; Economou, J S (1996) The adenoviral transcription factor, E1A 13S, trans-activates the human tumor necrosis factor-alpha promoter. Virus Res 40:65-74
Toloza, E M; Hunt, K; Swisher, S et al. (1996) In vivo cancer gene therapy with a recombinant interleukin-2 adenovirus vector. Cancer Gene Ther 3:11-7
Economou, J S; Belldegrun, A S; Glaspy, J et al. (1996) In vivo trafficking of adoptively transferred interleukin-2 expanded tumor-infiltrating lymphocytes and peripheral blood lymphocytes. Results of a double gene marking trial. J Clin Invest 97:515-21
Lee, J D; Rhoades, K; Economou, J S (1995) Interleukin-4 inhibits the expression of tumour necrosis factors alpha and beta, interleukins-1 beta and -6 and interferon-gamma. Immunol Cell Biol 73:57-61
Rhoades, K L; Cai, S; Golub, S H et al. (1995) Granulocyte-macrophage colony-stimulating factor and interleukin-4 differentially regulate the human tumor necrosis factor-alpha promoter region. Cell Immunol 161:125-31
Badie, B; Hunt, K; Economou, J S et al. (1994) Stereotactic delivery of a recombinant adenovirus into a C6 glioma cell line in a rat brain tumor model. Neurosurgery 35:910-5;discussion 915-6
Miller, A R; McBride, W H; Dubinett, S M et al. (1993) Transduction of human melanoma cell lines with the human interleukin-7 gene using retroviral-mediated gene transfer: comparison of immunologic properties with interleukin-2. Blood 82:3686-94
Lee, J D; Sievers, T M; Skotzko, M et al. (1992) Interleukin-6 production by human melanoma cell lines. Lymphokine Cytokine Res 11:161-6
Rhoades, K L; Golub, S H; Economou, J S (1992) The regulation of the human tumor necrosis factor alpha promoter region in macrophage, T cell, and B cell lines. J Biol Chem 267:22102-7

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