Phosphorylation and Htlv-II Rex Function

Green, Patrick Lee

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29CA059581-04
• Application #: 2100179
• Study Section: Virology Study Section (VR)
• Project Start: 1993-05-01
• Project End: 1998-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: Vanderbilt University Medical Center
• Department: Microbiology/Immun/Virology
• Type: Schools of Medicine
• DUNS #: 004413456
• City: Nashville
• State: TN
• Country: United States
• Zip Code: 37212

Publications

Narayan, M; Kusuhara, K; Green, P L (2001) Phosphorylation of two serine residues regulates human T-cell leukemia virus type 2 Rex function. J Virol 75:8440-8

Kusuhara, K; Anderson, M; Pettiford, S M et al. (1999) Human T-cell leukemia virus type 2 Rex protein increases stability and promotes nuclear to cytoplasmic transport of gag/pol and env RNAs. J Virol 73:8112-9

Mulloy, J C; Migone, T S; Ross, T M et al. (1998) Human and simian T-cell leukemia viruses type 2 (HTLV-2 and STLV-2(pan-p)) transform T cells independently of Jak/STAT activation. J Virol 72:4408-12

Ross, T M; Minella, A C; Fang, Z Y et al. (1997) Mutational analysis of human T-cell leukemia virus type 2 Tax. J Virol 71:8912-7

Ross, T M; Pettiford, S M; Green, P L (1996) The tax gene of human T-cell leukemia virus type 2 is essential for transformation of human T lymphocytes. J Virol 70:5194-202

Green, P L; Ross, T M; Chen, I S et al. (1995) Human T-cell leukemia virus type II nucleotide sequences between env and the last exon of tax/rex are not required for viral replication or cellular transformation. J Virol 69:387-94