Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29CA062034-02
Application #
2102992
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1995-01-01
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Nebraska Lincoln
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
555456995
City
Lincoln
State
NE
Country
United States
Zip Code
68588

  Publications

Swyka, Robert A; Berkowitz, David B (2017) The In Situ Enzymatic Screening (ISES) Approach to Reaction Discovery and Catalyst Identification. Curr Protoc Chem Biol 9:285-305
Berkowitz, David B; Karukurichi, Kannan R; de la Salud-Bea, Roberto et al. (2008) Use of Fluorinated Functionality in Enzyme Inhibitor Development: Mechanistic and Analytical Advantages. J Fluor Chem 129:731-742
Karukurichi, Kannan R; de la Salud-Bea, Roberto; Jahng, Wan Jin et al. (2007) Examination of the new alpha-(2'Z-fluoro)vinyl trigger with lysine decarboxylase: the absolute stereochemistry dictates the reaction course. J Am Chem Soc 129:258-9
Berkowitz, David B; Wu, Bin; Li, Huijie (2006) A formal [3,3]-sigmatropic rearrangement route to quaternary alpha-vinyl amino acids: use of allylic N-PMP trifluoroacetimidates. Org Lett 8:971-4
Berkowitz, David B; Bose, Mohua; Choi, Sungjo (2002) In situ enzymatic screening (ISES): a tool for catalyst discovery and reaction development. Angew Chem Int Ed Engl 41:1603-7