Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29CA067346-02
Application #
2111005
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1995-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Pollock, Sheri L; Rush, Elizabeth A; Redner, Robert L (2014) NPM-RAR, not the RAR-NPM reciprocal t(5;17)(q35;q21) acute promyelocytic leukemia fusion protein, inhibits myeloid differentiation. Leuk Lymphoma 55:1383-7
Dorritie, Kathleen A; Redner, Robert L; Johnson, Daniel E (2014) STAT transcription factors in normal and cancer stem cells. Adv Biol Regul 56:30-44
Rush, Elizabeth A; Schlesinger, Kimberly W; Watkins, Simon C et al. (2006) The NPM-RAR fusion protein associated with the t(5;17) variant of APL does not interact with PML. Leuk Res 30:979-86
Redner, R L; Chen, J D; Rush, E A et al. (2000) The t(5;17) acute promyelocytic leukemia fusion protein NPM-RAR interacts with co-repressor and co-activator proteins and exhibits both positive and negative transcriptional properties. Blood 95:2683-90
Redner, R L; Corey, S J; Rush, E A (1997) Differentiation of t(5;17) variant acute promyelocytic leukemic blasts by all-trans retinoic acid. Leukemia 11:1014-6
Redner, R L; Rush, E A; Faas, S et al. (1996) The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion. Blood 87:882-6