Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29GM038612-01
Application #
3466335
Study Section
Toxicology Study Section (TOX)
Project Start
1987-07-01
Project End
1991-06-30
Budget Start
1987-07-01
Budget End
1988-06-30
Support Year
1
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Arkansas at Fayetteville
Department
Type
Earth Sciences/Resources
DUNS #
191429745
City
Fayetteville
State
AR
Country
United States
Zip Code
72701
Glahn, R P; Bottje, W G; Maynard, P et al. (1993) Response of the avian kidney to acute changes in arterial perfusion pressure and portal blood supply. Am J Physiol 264:R428-34
Bottje, W G; Graupner, W G; Enkvetchakul, B et al. (1993) Prostacyclin elevation following glutathione depletion in vivo. Possible threshold dependency in liver and lung. Biochem Pharmacol 46:1019-27
Wideman Jr, R F; Glahn, R P; Bottje, W G et al. (1992) Use of a thermal pulse decay system to assess avian renal blood flow during reduced renal arterial perfusion pressure. Am J Physiol 262:R90-8
Bottje, W; Glahn, R; Beers, K et al. (1992) Effect of diethyl maleate on glutathione, hepatic and renal cortical perfusion, and portal 6-ketoPGF1 alpha and TxB2 levels in swine. Comp Biochem Physiol C 101:125-9
Nejad, H H; Bottje, W G (1992) Glutathione depletion and rabbit renal medulla 6-ketoPGF1 alpha and TxB2: levels in vivo and following homogenate incubation in vitro. Int J Biochem 24:561-4
Beers, K W; Glahn, R P; Bottje, W G et al. (1992) Aflatoxin and glutathione in domestic fowl (Gallus domesticus)--II. Effects on hepatic blood flow. Comp Biochem Physiol C 101:463-7
Beers, K W; Nejad, H; Bottje, W G (1992) Aflatoxin and glutathione in domestic fowl (Gallus domesticus)--I. Glutathione elevation and attenuation by high dietary methionine. Comp Biochem Physiol C 101:239-44
Maynard, P M; Graupner, W G; Bottje, W G (1992) Effect of glutathione depletion on tissue and plasma prostacyclin and thromboxane in rats. Biochem Pharmacol 43:1043-51
Glahn, R P; Beers, K W; Bottje, W G et al. (1991) Aflatoxicosis alters avian renal function, calcium, and vitamin D metabolism. J Toxicol Environ Health 34:309-21
Bottje, W; Glahn, R; Beers, K et al. (1991) Indomethacin attenuation of hepatic perfusion and plasma 6-ketoPGF1 alpha elevations following glutathione depletion in rabbits. Biochim Biophys Acta 1073:168-76

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