Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29HD031299-03
Application #
2203739
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1994-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Illinois Urbana-Champaign
Department
Physiology
Type
Schools of Arts and Sciences
DUNS #
041544081
City
Champaign
State
IL
Country
United States
Zip Code
61820
Kim, J; Petz, L N; Ziegler, Y S et al. (2000) Regulation of the estrogen-responsive pS2 gene in MCF-7 human breast cancer cells. J Steroid Biochem Mol Biol 74:157-68
Petz, L N; Nardulli, A M (2000) Sp1 binding sites and an estrogen response element half-site are involved in regulation of the human progesterone receptor A promoter. Mol Endocrinol 14:972-85
Romine, L E; Wood, J R; Lamia, L A et al. (1998) The high mobility group protein 1 enhances binding of the estrogen receptor DNA binding domain to the estrogen response element. Mol Endocrinol 12:664-74
Wood, J R; Greene, G L; Nardulli, A M (1998) Estrogen response elements function as allosteric modulators of estrogen receptor conformation. Mol Cell Biol 18:1927-34
Lazennec, G; Ediger, T R; Petz, L N et al. (1997) Mechanistic aspects of estrogen receptor activation probed with constitutively active estrogen receptors: correlations with DNA and coregulator interactions and receptor conformational changes. Mol Endocrinol 11:1375-86
Ozers, M S; Hill, J J; Ervin, K et al. (1997) Equilibrium binding of estrogen receptor with DNA using fluorescence anisotropy. J Biol Chem 272:30405-11
Kim, J; de Haan, G; Nardulli, A M et al. (1997) Prebending the estrogen response element destabilizes binding of the estrogen receptor DNA binding domain. Mol Cell Biol 17:3173-80
Petz, L N; Nardulli, A M; Kim, J et al. (1997) DNA bending is induced by binding of the glucocorticoid receptor DNA binding domain and progesterone receptors to their response element. J Steroid Biochem Mol Biol 60:31-41
Potthoff, S J; Romine, L E; Nardulli, A M (1996) Effects of wild type and mutant estrogen receptors on DNA flexibility, DNA bending, and transcription activation. Mol Endocrinol 10:1095-106
Nardulli, A M; Romine, L E; Carpo, C et al. (1996) Estrogen receptor affinity and location of consensus and imperfect estrogen response elements influence transcription activation of simplified promoters. Mol Endocrinol 10:694-704

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