In order to diagnose and cure central visual losses (e.g., in a patient who is unable to properly perceive visual motion) we must first gain an understanding of the neural processing in visual cortex. The long-term goal of this research is to develop a detailed, quantitative, predictive model of cell function in primary visual cortex. We will have succeeded when/if we can record from a cell while presenting a fixed set of visual stimuli (to measure model parameters), and then be able to predict the cell's response to any visual stimulus. The computational/theoretical research proposed in this application is designed to complement empirical research by clarifying the interpretation of experimental results and by making a number of empirically testable predictions thereby suggesting new experiments. Specifically, we aim to: (1) Reconcile the controversy regarding the origin of selectivity of simple and complex cells; (2) Reconcile the controversy over the role of intracortical (e.g., cross-orientation) suppression; (3) Explain the variability, from cell to cell, of contrast-response data.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29MH050228-02
Application #
2249554
Study Section
Cognitive Functional Neuroscience Review Committee (CFN)
Project Start
1993-01-01
Project End
1997-12-31
Budget Start
1994-01-01
Budget End
1994-12-31
Support Year
2
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Stanford University
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
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