Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29NS031939-03
Application #
2269908
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1994-04-01
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
State University of New York at Buffalo
Department
Other Health Professions
Type
Schools of Pharmacy
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260

  Publications

Boje, Kathleen M K; Jaworowicz Jr, David; Raybon, Joseph J (2003) Neuroinflammatory role of prostaglandins during experimental meningitis: evidence suggestive of an in vivo relationship between nitric oxide and prostaglandins. J Pharmacol Exp Ther 304:319-25
Raybon, J J; Boje, K M (2001) A critical evaluation of the brain efflux index method as applied to the nitric oxide synthase inhibitor, aminoguanidine. Biopharm Drug Dispos 22:391-401
Mahar Doan, K M; Boje, K M (2000) Theoretical pharmacokinetic and pharmacodynamic simulations of drug delivery mediated by blood--brain barrier transporters. Biopharm Drug Dispos 21:261-78
Mahar Doan, K M; Ng, S; Boje, K M (2000) Cellular transport processes of aminoguanidine, a nitric oxide synthase inhibitor, in the opossum kidney cell culture line. Int J Pharm 194:209-20
Boje, K M; Lakhman, S S (2000) Nitric oxide redox species exert differential permeability effects on the blood-brain barrier. J Pharmacol Exp Ther 293:545-50
Mahar Doan, K M; Lakhman, S S; Boje, K M (2000) Blood-brain barrier transport studies of organic guanidino cations using an in situ brain perfusion technique. Brain Res 876:141-7
Jaworowicz Jr, D J; Filipowski, M T; Boje, K M (1999) Improved high-performance liquid chromatographic assay for nimesulide. J Chromatogr B Biomed Sci Appl 723:293-9
Jaworowicz Jr, D J; Korytko, P J; Singh Lakhman, S et al. (1998) Nitric oxide and prostaglandin E2 formation parallels blood-brain barrier disruption in an experimental rat model of bacterial meningitis. Brain Res Bull 46:541-6
Boje, K M (1996) Inhibition of nitric oxide synthase attenuates blood-brain barrier disruption during experimental meningitis. Brain Res 720:75-83
Korytko, P J; Boje, K M (1996) Pharmacological characterization of nitric oxide production in a rat model of meningitis. Neuropharmacology 35:231-7

Showing the most recent 10 out of 13 publications