Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI042266-07
Application #
6687764
Study Section
Special Emphasis Panel (ZRG1-EI (02))
Program Officer
Kirkham, Perry M
Project Start
1998-01-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
7
Fiscal Year
2004
Total Cost
$572,192
Indirect Cost

  Institution

Name
Scripps Research Institute
Department
Type
DUNS #
781613492
City
La Jolla
State
CA
Country
United States
Zip Code
92037

  Publications

Collins, Bernard C; Nakahara, Hiro; Acharya, Sharmistha et al. (2017) Crystal structure of an anti-idiotype variable lymphocyte receptor. Acta Crystallogr F Struct Biol Commun 73:682-687
Das, Nabanita; Dewan, Varun; Grace, Peter M et al. (2016) HMGB1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia. Cell Rep 17:1128-1140
Baranczak, Aleksandra; Liu, Yu; Connelly, Stephen et al. (2015) A fluorogenic aryl fluorosulfate for intraorganellar transthyretin imaging in living cells and in Caenorhabditis elegans. J Am Chem Soc 137:7404-14
Lockner, Jonathan W; Eubanks, Lisa M; Choi, Jennifer L et al. (2015) Flagellin as carrier and adjuvant in cocaine vaccine development. Mol Pharm 12:653-62
Jiménez-Dalmaroni, Maximiliano J; Radcliffe, Catherine M; Harvey, David J et al. (2015) Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids. Innate Immun 21:175-93
Penchala, Sravan C; Connelly, Stephen; Wang, Yu et al. (2013) AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin. Proc Natl Acad Sci U S A 110:9992-7
Grimster, Neil P; Connelly, Stephen; Baranczak, Aleksandra et al. (2013) Aromatic sulfonyl fluorides covalently kinetically stabilize transthyretin to prevent amyloidogenesis while affording a fluorescent conjugate. J Am Chem Soc 135:5656-68
Lee, Ji Yeon; Kim, Hyoun Sook; Baek, In Wha et al. (2013) Overexpression, crystallization and preliminary X-ray crystallographic analysis of the variable lymphocyte receptor 2913 ectodomain fused with internalin B. Acta Crystallogr Sect F Struct Biol Cryst Commun 69:39-41
Hong, Minsun; Yoon, Sung-il; Wilson, Ian A (2012) Structure and functional characterization of the RNA-binding element of the NLRX1 innate immune modulator. Immunity 36:337-47
Bulawa, Christine E; Connelly, Stephen; Devit, Michael et al. (2012) Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. Proc Natl Acad Sci U S A 109:9629-34

Showing the most recent 10 out of 66 publications