Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA048023-09
Application #
2092862
Study Section
Experimental Immunology Study Section (EI)
Project Start
1989-03-01
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Minn, A J; Kettlun, C S; Liang, H et al. (1999) Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms. EMBO J 18:632-43
Arch, R H; Thompson, C B (1999) Lymphocyte survival--the struggle against death. Annu Rev Cell Dev Biol 15:113-40
Funk, P E; Thompson, C B (1998) Identification of a lectin that induces cell death in developing chicken B cells. Cell Immunol 186:75-81
Sattler, M; Liang, H; Nettesheim, D et al. (1997) Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis. Science 275:983-6
Funk, P E; Tregaskes, C A; Young, J R et al. (1997) The avian chB6 (Bu-1) alloantigen can mediate rapid cell death. J Immunol 159:1695-702
Noel, P J; Boise, L H; Thompson, C B (1996) Regulation of T cell activation by CD28 and CTLA4. Adv Exp Med Biol 406:209-17
Masteller, E L; Larsen, R D; Carlson, L M et al. (1995) Chicken B cells undergo discrete developmental changes in surface carbohydrate structure that appear to play a role in directing lymphocyte migration during embryogenesis. Development 121:1657-67
Masteller, E L; Lee, K P; Carlson, L M et al. (1995) Expression of sialyl Lewis(x) and Lewis(x) defines distinct stages of chicken B cell maturation. J Immunol 155:5550-6
Pandey, A; Tjoelker, L W; Thompson, C B (1993) Restricted immunoglobulin junctional diversity in neonatal B cells results from developmental selection rather than homology-based V(D)J joining. J Exp Med 177:329-37
McCormack, W T; Hurley, E A; Thompson, C B (1993) Germ line maintenance of the pseudogene donor pool for somatic immunoglobulin gene conversion in chickens. Mol Cell Biol 13:821-30

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