Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DA002854-17
Application #
2116655
Study Section
Special Emphasis Panel (NSS)
Project Start
1993-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California San Diego
Department
Psychiatry
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093

  Publications

Kuczenski, Ronald; Everall, Ian P; Crews, Leslie et al. (2007) Escalating dose-multiple binge methamphetamine exposure results in degeneration of the neocortex and limbic system in the rat. Exp Neurol 207:42-51
Clark, Robert E; Kuczenski, Ronald; Segal, David S (2007) Escalating dose, multiple binge methamphetamine regimen does not impair recognition memory in rats. Synapse 61:515-22
Shilling, Paul D; Kuczenski, Ronald; Segal, David S et al. (2006) Differential regulation of immediate-early gene expression in the prefrontal cortex of rats with a high vs low behavioral response to methamphetamine. Neuropsychopharmacology 31:2359-67
O'Neil, Meghan L; Kuczenski, Ronald; Segal, David S et al. (2006) Escalating dose pretreatment induces pharmacodynamic and not pharmacokinetic tolerance to a subsequent high-dose methamphetamine binge. Synapse 60:465-73
Segal, David S; Kuczenski, Ronald (2006) Human methamphetamine pharmacokinetics simulated in the rat: single daily intravenous administration reveals elements of sensitization and tolerance. Neuropsychopharmacology 31:941-55
Segal, David S; Kuczenski, Ronald; O'Neil, Meghan L et al. (2005) Prolonged exposure of rats to intravenous methamphetamine: behavioral and neurochemical characterization. Psychopharmacology (Berl) 180:501-12
Kuczenski, Ronald; Segal, David S (2005) Stimulant actions in rodents: implications for attention-deficit/hyperactivity disorder treatment and potential substance abuse. Biol Psychiatry 57:1391-6
Segal, David S; Kuczenski, Ronald; O'Neil, Meghan L et al. (2003) Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge. Neuropsychopharmacology 28:1730-40
Capani, F; Deerinck, T J; Ellisman, M H et al. (2001) Phalloidin-eosin followed by photo-oxidation: a novel method for localizing F-actin at the light and electron microscopic levels. J Histochem Cytochem 49:1351-61
Capani, F; Ellisman, M H; Martone, M E (2001) Filamentous actin is concentrated in specific subpopulations of neuronal and glial structures in rat central nervous system. Brain Res 923:1-11

Showing the most recent 10 out of 48 publications