Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DE006153-24
Application #
7056192
Study Section
Special Emphasis Panel (NSS)
Program Officer
Lunsford, Dwayne
Project Start
1982-08-01
Project End
2008-04-30
Budget Start
2006-05-01
Budget End
2007-04-30
Support Year
24
Fiscal Year
2006
Total Cost
$561,199
Indirect Cost
Name
Forsyth Institute
Department
Type
DUNS #
062190616
City
Cambridge
State
MA
Country
United States
Zip Code
02142
Stipp, Rafael N; Boisvert, Heike; Smith, Daniel J et al. (2013) CovR and VicRK regulate cell surface biogenesis genes required for biofilm formation in Streptococcus mutans. PLoS One 8:e58271
Duque, Cristiane; Stipp, Rafael N; Wang, Bing et al. (2011) Downregulation of GbpB, a component of the VicRK regulon, affects biofilm formation and cell surface characteristics of Streptococcus mutans. Infect Immun 79:786-96
Peacock, Zachary S; Cox, Darren; Schmidt, Brian L (2010) Involvement of PTCH1 mutations in the calcifying epithelial odontogenic tumor. Oral Oncol 46:387-92
Smith, Daniel J (2010) Dental caries vaccines: prospects and concerns. Expert Rev Vaccines 9:1-3
Klein, Marlise I; Bang, Sungyon; Florio, Flavia M et al. (2006) Genetic diversity of competence gene loci in clinical genotypes of Streptococcus mutans. J Clin Microbiol 44:3015-20
Mattos-Graner, Renata O; Porter, Kristen A; Smith, Daniel J et al. (2006) Functional analysis of glucan binding protein B from Streptococcus mutans. J Bacteriol 188:3813-25
Peacock, Z S; Barnes, L A; King, W F et al. (2005) Influence of microparticle formulation on immunogenicity of SYI, a synthetic peptide derived from Streptococcus mutans GbpB. Oral Microbiol Immunol 20:60-4
Smith, Daniel J; King, William F; Rivero, Joy et al. (2005) Immunological and protective effects of diepitopic subunit dental caries vaccines. Infect Immun 73:2797-804
Russell, Michael W; Childers, Noel K; Michalek, Suzanne M et al. (2004) A Caries Vaccine? The state of the science of immunization against dental caries. Caries Res 38:230-5
Mattos-Graner, Renata O; Napimoga, Marcelo H; Fukushima, Kasuo et al. (2004) Comparative analysis of Gtf isozyme production and diversity in isolates of Streptococcus mutans with different biofilm growth phenotypes. J Clin Microbiol 42:4586-92

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