Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37DK037034-18
Application #
6687379
Study Section
Special Emphasis Panel (NSS)
Program Officer
Doo, Edward
Project Start
1986-05-01
Project End
2008-04-30
Budget Start
2003-07-15
Budget End
2004-04-30
Support Year
18
Fiscal Year
2003
Total Cost
$544,357
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

DeHart, David N; Lemasters, John J; Maldonado, Eduardo N (2018) Erastin-Like Anti-Warburg Agents Prevent Mitochondrial Depolarization Induced by Free Tubulin and Decrease Lactate Formation in Cancer Cells. SLAS Discov 23:23-33
Liu, Qinlong; Rehman, Hasibur; Krishnasamy, Yasodha et al. (2017) 8-pCPT-cGMP prevents mitochondrial depolarization and improves the outcome of steatotic partial liver transplantation. Int J Physiol Pathophysiol Pharmacol 9:69-83
Hendriks, Giel; Derr, Remco S; Misovic, Branislav et al. (2016) The Extended ToxTracker Assay Discriminates Between Induction of DNA Damage, Oxidative Stress, and Protein Misfolding. Toxicol Sci 150:190-203
Rehman, Hasibur; Liu, Qinlong; Krishnasamy, Yasodha et al. (2016) The mitochondria-targeted antioxidant MitoQ attenuates liver fibrosis in mice. Int J Physiol Pathophysiol Pharmacol 8:14-27
Maldonado, Eduardo N; DeHart, David N; Patnaik, Jyoti et al. (2016) ATP/ADP Turnover and Import of Glycolytic ATP into Mitochondria in Cancer Cells Is Independent of the Adenine Nucleotide Translocator. J Biol Chem 291:19642-50
Hu, Jiangting; Ramshesh, Venkat K; McGill, Mitchell R et al. (2016) Low Dose Acetaminophen Induces Reversible Mitochondrial Dysfunction Associated with Transient c-Jun N-Terminal Kinase Activation in Mouse Liver. Toxicol Sci 150:204-15
Krishnasamy, Yasodha; Ramshesh, Venkat K; Gooz, Monika et al. (2016) Ethanol and High Cholesterol Diet Causes Severe Steatohepatitis and Early Liver Fibrosis in Mice. PLoS One 11:e0163342
Belosludtsev, Konstantin N; Belosludtseva, Natalia V; Agafonov, Alexey V et al. (2015) Effect of surface-potential modulators on the opening of lipid pores in liposomal and mitochondrial inner membranes induced by palmitate and calcium ions. Biochim Biophys Acta 1848:2200-5
Liu, Qinlong; Krishnasamy, Yasodha; Rehman, Hasibur et al. (2015) Disrupted Renal Mitochondrial Homeostasis after Liver Transplantation in Rats. PLoS One 10:e0140906
Liu, Qinlong; Rehman, Hasibur; Krishnasamy, Yasodha et al. (2015) Improvement of liver injury and survival by JNK2 and iNOS deficiency in liver transplants from cardiac death mice. J Hepatol 63:68-74

Showing the most recent 10 out of 168 publications