Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM027309-18
Application #
2174923
Study Section
Special Emphasis Panel (NSS)
Project Start
1979-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Biochemistry
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Zheng, Zhong; Dutton, P Leslie; Gunner, M R (2010) The measured and calculated affinity of methyl- and methoxy-substituted benzoquinones for the Q(A) site of bacterial reaction centers. Proteins 78:2638-54
Chobot, Sarah E; Zhang, Haibo; Moser, Christopher C et al. (2008) Breaking the Q-cycle: finding new ways to study Qo through thermodynamic manipulations. J Bioenerg Biomembr 40:501-7
Zhang, Haibo; Osyczka, Artur; Dutton, P Leslie et al. (2007) Exposing the complex III Qo semiquinone radical. Biochim Biophys Acta 1767:883-7
Osyczka, Artur; Zhang, Haibo; Mathe, Christelle et al. (2006) Role of the PEWY glutamate in hydroquinone-quinone oxidation-reduction catalysis in the Qo Site of cytochrome bc1. Biochemistry 45:10492-503
Zhang, Haibo; Osyczka, Artur; Moser, Christopher C et al. (2006) Resilience of Rhodobacter sphaeroides cytochrome bc1 to heme c1 ligation changes. Biochemistry 45:14247-55
Moser, Christopher C; Farid, Tammer A; Chobot, Sarah E et al. (2006) Electron tunneling chains of mitochondria. Biochim Biophys Acta 1757:1096-109
Iwaki, Masayo; Yakovlev, Gregory; Hirst, Judy et al. (2005) Direct observation of redox-linked histidine protonation changes in the iron-sulfur protein of the cytochrome bc1 complex by ATR-FTIR spectroscopy. Biochemistry 44:4230-7
Osyczka, Artur; Moser, Christopher C; Dutton, P Leslie (2005) Fixing the Q cycle. Trends Biochem Sci 30:176-82
Osyczka, Artur; Moser, Christopher C; Dutton, P Leslie (2004) Novel cyanide inhibition at cytochrome c1 of Rhodobacter capsulatus cytochrome bc1. Biochim Biophys Acta 1655:71-6
Iwaki, Masayo; Osyczka, Artur; Moser, Christopher C et al. (2004) ATR-FTIR spectroscopy studies of iron-sulfur protein and cytochrome c1 in the Rhodobacter capsulatus cytochrome bc1 complex. Biochemistry 43:9477-86

Showing the most recent 10 out of 54 publications