Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37GM034821-20
Application #
6692871
Study Section
Special Emphasis Panel (NSS)
Program Officer
Shapiro, Bert I
Project Start
1985-04-01
Project End
2009-03-31
Budget Start
2004-04-01
Budget End
2005-03-31
Support Year
20
Fiscal Year
2004
Total Cost
$551,594
Indirect Cost

  Institution

Name
Princeton University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
002484665
City
Princeton
State
NJ
Country
United States
Zip Code
08544

  Publications

Lee, James; Sutterlin, Holly A; Wzorek, Joseph S et al. (2018) Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion. Proc Natl Acad Sci U S A 115:2359-2364
Grabowicz, Marcin; Silhavy, Thomas J (2017) Envelope Stress Responses: An Interconnected Safety Net. Trends Biochem Sci 42:232-242
May, Kerrie L; Silhavy, Thomas J (2017) Making a membrane on the other side of the wall. Biochim Biophys Acta Mol Cell Biol Lipids 1862:1386-1393
Okuda, Suguru; Sherman, David J; Silhavy, Thomas J et al. (2016) Lipopolysaccharide transport and assembly at the outer membrane: the PEZ model. Nat Rev Microbiol 14:337-45
Sutterlin, Holly A; Shi, Handuo; May, Kerrie L et al. (2016) Disruption of lipid homeostasis in the Gram-negative cell envelope activates a novel cell death pathway. Proc Natl Acad Sci U S A 113:E1565-74
Lee, James; Xue, Mingyu; Wzorek, Joseph S et al. (2016) Characterization of a stalled complex on the ?-barrel assembly machine. Proc Natl Acad Sci U S A 113:8717-22
Soltes, Garner R; Schwalm, Jaclyn; Ricci, Dante P et al. (2016) The Activity of Escherichia coli Chaperone SurA Is Regulated by Conformational Changes Involving a Parvulin Domain. J Bacteriol 198:921-9
Konovalova, Anna; Mitchell, Angela M; Silhavy, Thomas J (2016) A lipoprotein/?-barrel complex monitors lipopolysaccharide integrity transducing information across the outer membrane. Elife 5:
Grabowicz, Marcin; Koren, Daria; Silhavy, Thomas J (2016) The CpxQ sRNA Negatively Regulates Skp To Prevent Mistargeting of ?-Barrel Outer Membrane Proteins into the Cytoplasmic Membrane. MBio 7:e00312-16
Mahoney, Tara F; Ricci, Dante P; Silhavy, Thomas J (2016) Classifying ?-Barrel Assembly Substrates by Manipulating Essential Bam Complex Members. J Bacteriol 198:1984-92

Showing the most recent 10 out of 90 publications